Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 1/20 | 0.36 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.36 |
| ▸ | ESR1 | P03372 | 1/20 | 0.32 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.32 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | ACHE | P22303 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | CASP3 | P42574 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.31 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.31 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.31 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.31 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.31 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8850555 | 0.84 | GABRA1 (0.36) | GABRA1GABRB2ESR1ESR2LMNA | |
| SCHEMBL2572622 | 0.84 | ESR1 (0.32) | GABRA1GABRB2ESR1ESR2ACHE | |
| SCHEMBL9954732 | 0.82 | NFE2L2 (0.33) | — | |
| SCHEMBL9221768 | 0.82 | ACHE (0.35) | ACHENPC1RAB9AHDAC8ALDH1A1 | |
| SCHEMBL14094919 | 0.77 | NPC1 (0.41) | GABRA1GABRB2ESR1ESR2RIPK1 | |
| SCHEMBL34924 | 0.76 | ESR1 (0.36) | GABRA1GABRB2ESR1ESR2ACHE | |
| SCHEMBL6240842 | 0.74 | ESR1 (0.31) | GABRA1GABRB2ESR1ESR2RIPK1 | |
| SCHEMBL28028536 | 0.74 | KCNN4 (0.38) | RIPK1ACHEHDAC2 | |
| SCHEMBL12050426 | 0.72 | ESR1 (0.33) | ESR1ESR2HDAC4HDAC2HDAC8 | |
| SCHEMBL2494913 | 0.72 | ESR1 (0.33) | ESR1ESR2HDAC4HDAC2HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7504459-B2 | Methacrylate amide acetals in coatings | E.I. DU PONT DE NEMOURS & COMPANY (US) | 2009-03-17 | — | — | US | disclosed |