SCHEMBL13428212

SCHEMBL13428212

N#C/C(=C\c1cc2c3c(c1)CCCN3CCC2)C(=O)O

nearest known ligand 0.60

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
▸ SLC16A3 O15427 3/20 0.47
▸ SLC16A1 P53985 3/20 0.47
▸ EGFR P00533 2/20 0.44
▸ KDM4E B2RXH2 2/20 0.44
▸ CISD1 Q9NZ45 1/20 0.44
▸ ALDH1A1 P00352 1/20 0.44
▸ CYP3A4 P08684 1/20 0.44
▸ HPGD P15428 1/20 0.44
▸ GPR35 Q9HC97 1/20 0.44
▸ RAD52 P43351 1/20 0.41
▸ KMT2A Q03164 1/20 0.41
▸ RXFP1 Q9HBX9 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL597887 1.00 SLC16A3 (0.47) SLC16A3SLC16A1EGFRKDM4ECISD1
SCHEMBL14540647 1.00 SLC16A3 (0.47) SLC16A3SLC16A1EGFRKDM4ECISD1
SCHEMBL16301917 0.88 MAPT (0.51) EGFRKDM4EALDH1A1HPGDGPR35
SCHEMBL12305833 0.85 SLC16A3 (0.43) SLC16A3SLC16A1EGFRKDM4ECISD1
SCHEMBL23373774 0.84 ALDH1A1 (0.49) SLC16A3SLC16A1EGFRKDM4EALDH1A1
SCHEMBL10253234 0.84 ALDH1A1 (0.44) EGFRKDM4EALDH1A1HPGDRAD52
SCHEMBL597755 0.81 KMT2A (0.55) EGFRKDM4ECISD1ALDH1A1CYP3A4
SCHEMBL14703464 0.79 ALDH1A1 (0.50) ALDH1A1HPGDKMT2ARXFP1
SCHEMBL15491206 0.78 ALDH1A1 (0.47) KDM4EALDH1A1HPGDKMT2A
SCHEMBL1779715 0.77 APP (0.53) KDM4EALDH1A1CYP3A4HPGDKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 62 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4427033-B1 METHOD FOR QUALITATIVE AND QUANTITATIVE DETERMINATION OF PROTEIN AGGREGATES PAIA BIOTECH GMBH (DE) 2026-05-20 — — EP claimed
CN-119688656-A Fluorescence detection method for amylase activity, application and microfluidic detection device 上海交通大学医学院附属瑞金医院 2025-03-25 — — CN claimed
EP-4427033-A1 METHOD FOR THE QUALITATIVE AND QUANTITATIVE DETERMINATION OF PROTEIN AGGREGATES PAIA Biotech GmbH (DE) 2024-09-11 — — EP claimed
CN-117229285-B Synthesis and application of fluorescent probe for simultaneously distinguishing and detecting homocysteine and amyloid oligomer 湖南师范大学 2024-07-16 — — CN claimed
CN-116625995-A Application of 9- (2-carboxyl-2-cyanovinyl) julolidine in analysis of content of direct and amylopectin and ratio thereof 中国农业大学 2023-08-22 — — CN claimed
EP-4211264-A1 COMPOSITIONS AND METHODS FOR DETECTING AN ABASIC SITE OF A NUCLEIC ACID Illumina, Inc. (US) 2023-07-19 — — EP claimed
WO-2023079052-A1 METHOD FOR THE QUALITATIVE AND QUANTITATIVE DETERMINATION OF PROTEIN AGGREGATES PAIA BIOTECH GMBH (DE) 2023-05-11 — — WO claimed
CN-115803451-A Compositions and methods for detecting abasic sites of nucleic acids 伊鲁米纳公司 2023-03-14 — — CN claimed
EP-2802871-B1 CHARACTERIZATION OF SUBVISIBLE PARTICLES USING A PARTICLE ANALYZER TAKEDA PHARMACEUTICALS CO (JP) 2022-07-27 — — EP claimed
CN-114444568-A Unsatisfied reason tracing method based on improved clustering algorithm 福建新大陆软件工程有限公司 2022-05-06 — — CN claimed
WO-2022056169-A1 COMPOSITIONS AND METHODS FOR DETECTING AN ABASIC SITE OF A NUCLEIC ACID ILLUMINA, INC (US) 2022-03-17 — — WO claimed
EP-4427033-B1 METHOD FOR QUALITATIVE AND QUANTITATIVE DETERMINATION OF PROTEIN AGGREGATES PAIA BIOTECH GMBH (DE) 2026-05-20 — — EP disclosed
US-12613246-B2 Fluorescent probe and protein labeling method FLUORESCENCE DIAGNOSIS (SHANGHAI) BIOTECH COMPANY LTD. (CN) 2026-04-28 — — US disclosed
US-12596125-B2 Nano-rheological biomarkers for early and improved follow-up of pathologies associated to RBC deformability alteration ALCEDIAG (FR) 2026-04-07 — — US disclosed
US-12392782-B2 Characterization of protein binding to per- and polyfluoroalkyl substances NORTH CAROLINA STATE UNIVERSITY (US) 2025-08-19 — — US disclosed
US-20100059740-A1 POLYMERIC ANIONS/CATIONS MERCK PATENT GMBH (DE) 2010-03-11 — — US disclosed
EP-1311001-B1 DYE-SENSITIZED PHOTOELECTRIC TRANSDUCER NIPPON KAYAKU KK (JP) 2009-12-09 — — EP disclosed
WO-2008087031-A1 POLYMERIC ANIONS/CATIONS MERCK PATENT GMBH (DE) 2008-07-24 — — WO disclosed
US-20080110497-A1 Modified Titanium Oxide Microparticle and Photoelectric Transducer Making Use of the Same NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2008-05-15 — — US disclosed
US-20080110497-A1 Modified Titanium Oxide Microparticle and Photoelectric Transducer Making Use of the Same NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2008-05-15 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12613246-B2 Fluorescent probe and protein labeling method CYFIP1, IK, CYFIP2 SLC16A3 4858/4885SLC16A1 4354/4885EGFR 2822/4885
US-12596125-B2 Nano-rheological biomarkers for early and improved follow-up of pathologies associated to RBC deformability alteration SPTBN1, MB, HBZ SLC16A3 3722/4885SLC16A1 3819/4885EGFR 3790/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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