SCHEMBL597755

SCHEMBL597755

N#CC(C#N)=Cc1cc2c3c(c1)CCCN3CCC2

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ KMT2A Q03164 14/20 0.55
▸ MEN1 O00255 12/20 0.55
▸ ALDH1A1 P00352 9/20 0.55
▸ MAPT P10636 9/20 0.55
▸ SMN1; SMN2 Q16637 6/20 0.55
▸ CRHBP P24387 1/20 0.48
▸ HTT P42858 1/20 0.48
▸ CRHR2 Q13324 1/20 0.48
▸ LMNA P02545 7/20 0.44
▸ EGFR P00533 7/20 0.44
▸ TNNI3 P19429 1/20 0.44
▸ TNNT2 P45379 1/20 0.44
▸ TNNC1 P63316 1/20 0.44
▸ BLM P54132 6/20 0.43
▸ KDM4E B2RXH2 5/20 0.43
▸ HPGD P15428 5/20 0.43
▸ NPSR1 Q6W5P4 4/20 0.43
▸ CYP3A4 P08684 4/20 0.43
▸ CYP2C9 P11712 4/20 0.43
▸ ALOX15 P16050 4/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13428212 0.81 SLC16A3 (0.47) KMT2AALDH1A1EGFRKDM4EHPGD
SCHEMBL14540647 0.81 SLC16A3 (0.47) KMT2AALDH1A1EGFRKDM4EHPGD
SCHEMBL597887 0.81 SLC16A3 (0.47) KMT2AALDH1A1EGFRKDM4EHPGD
SCHEMBL1227300 0.81 KMT2A (0.56) KMT2AMEN1ALDH1A1MAPTSMN1; SMN2
SCHEMBL16301917 0.80 MAPT (0.51) KMT2AMEN1ALDH1A1MAPTSMN1; SMN2
SCHEMBL24043357 0.78 KMT2A (0.46) KMT2AMEN1ALDH1A1MAPTSMN1; SMN2
SCHEMBL23373774 0.77 ALDH1A1 (0.49) KMT2AMEN1ALDH1A1MAPTSMN1; SMN2
SCHEMBL24605624 0.77 NQO2 (0.43) KMT2AMEN1ALDH1A1MAPTSMN1; SMN2
SCHEMBL10253234 0.77 ALDH1A1 (0.44) KMT2AMEN1ALDH1A1MAPTSMN1; SMN2
SCHEMBL13989159 0.75 KMT2A (0.53) KMT2AMEN1ALDH1A1MAPTHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 115 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4427033-B1 METHOD FOR QUALITATIVE AND QUANTITATIVE DETERMINATION OF PROTEIN AGGREGATES PAIA BIOTECH GMBH (DE) 2026-05-20 — — EP claimed
EP-4662484-A1 MULTISENSOR ARRAYS, MULTISENSOR SYSTEMS AND RELATED METHODS Linxens Holding (FR) 2025-12-17 — — EP claimed
CN-112639470-B Diagnostic method for amyloid-related disease 阿米罗伊迪亚瑞典股份公司 2025-02-25 — — CN claimed
EP-4427033-A1 METHOD FOR THE QUALITATIVE AND QUANTITATIVE DETERMINATION OF PROTEIN AGGREGATES PAIA Biotech GmbH (DE) 2024-09-11 — — EP claimed
US-12076406-B2 Conjugates for targeting and clearing aggregates MEDIMMUNE LIMITED (GB) 2024-09-03 — — US claimed
WO-2024165881-A1 MULTISENSOR ARRAYS, MULTISENSOR SYSTEMS AND RELATED METHODS LINXENS HOLDING (FR) 2024-08-15 — — WO claimed
EP-3913010-B1 SIMPLIFIED METHOD FOR POLYURETHANE SYNTHESIS CONTROL BASED ON THE USE OF FLUORESCENT PROBES UNIV PISA (IT) 2024-06-19 — — EP claimed
EP-3775884-B1 METHOD FOR THE DIAGNOSIS OF AMYLOID-ASSOCIATED DISEASES AMYLOIDIA SWEDEN AB (SE) 2024-05-08 — — EP claimed
CN-117969472-A Method for high-throughput determination of heat stability and iron saturation of lactoferrin 陕西科技大学 2024-05-03 — — CN claimed
CN-116413167-A Blood analyzer 深圳市瑞图生物技术有限公司 2023-07-11 — — CN claimed
WO-2023079052-A1 METHOD FOR THE QUALITATIVE AND QUANTITATIVE DETERMINATION OF PROTEIN AGGREGATES PAIA BIOTECH GMBH (DE) 2023-05-11 — — WO claimed
CN-115855902-A Method and material for detecting concentration of tricresyl phosphate in water body 西南交通大学 2023-03-28 — — CN claimed
CN-115494038-A In-situ quick detection method for stability of nano-emulsion-based dispersion system and application 江南大学 2022-12-20 — — CN claimed
EP-2802871-B1 CHARACTERIZATION OF SUBVISIBLE PARTICLES USING A PARTICLE ANALYZER TAKEDA PHARMACEUTICALS CO (JP) 2022-07-27 — — EP claimed
US-20220026446-A1 METHOD FOR THE DIAGNOSIS OF AMYLOID-ASSOCIATED DISEASES AMYLOIDIA SWEDEN AB (SE) 2022-01-27 — — US claimed
WO-2016001644-A1 DIAGNOSIS AND TREATMENT OF NEURODEGENERATIVE DISORDERS CAMBRIDGE ENTERPRISE LIMITED (GB) 2016-01-07 — — WO claimed
EP-2802871-A2 CHARACTERIZATION OF SUBVISIBLE PARTICLES USING A PARTICLE ANALYZER Baxter International Inc (US) 2014-11-19 — — EP claimed
WO-2013106772-A2 CHARACTERIZATION OF SUBVISIBLE PARTICLES USING A PARTICLE ANALYZER BAXTER INTERNATIONAL, INC. (US) 2013-07-18 — — WO claimed
EP-4427033-B1 METHOD FOR QUALITATIVE AND QUANTITATIVE DETERMINATION OF PROTEIN AGGREGATES PAIA BIOTECH GMBH (DE) 2026-05-20 — — EP disclosed
WO-2005073697-A1 LOCAL FLOW AND SHEAR STRESS SENSOR BASED ON MOLECULAR ROTORS THE CURATORS OF THE UNIVERSITY OF MISSOURI (US) 2005-08-11 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12076406-B2 Conjugates for targeting and clearing aggregates FCGR2A, FCGR3B, FCGR1A KMT2A 2666/4885MEN1 2195/4885ALDH1A1 4265/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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