SCHEMBL13428351

SCHEMBL13428351

c1ccc(-c2c3cccc(N4c5ccccc5Oc5ccccc54)c3c(-c3ccccc3)c3cccc(N4c5ccccc5Oc5ccccc54)c23)cc1

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
P2RX4 Q99571 11/20 0.37
P2RX1 P51575 1/20 0.35
P2RX3 P56373 1/20 0.35
CYP2C9 P11712 3/20 0.33
CYP1A2 P05177 2/20 0.33
CYP3A4 P08684 2/20 0.33
CYP2C19 P33261 2/20 0.33
ALDH1A1 P00352 2/20 0.33
HPGD P15428 2/20 0.33
HSD17B10 Q99714 2/20 0.33
ESR1 P03372 1/20 0.33
ESR2 Q92731 1/20 0.33
KDM4E B2RXH2 1/20 0.33
LMNA P02545 1/20 0.33
POLB P06746 1/20 0.33
MAPT P10636 1/20 0.33
TSHR P16473 1/20 0.33
PDE6D O43924 1/20 0.32
EGFR P00533 1/20 0.31
ALOX15 P16050 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13428385 0.90 P2RX4 (0.37) P2RX4P2RX1P2RX3CYP2C9CYP1A2
SCHEMBL13428350 0.82 SMN1; SMN2 (0.36) CYP1A2ESR1ESR2KDM4EMAPT
SCHEMBL13540633 0.82
SCHEMBL13428344 0.80 POLB (0.41) P2RX4ALDH1A1HPGDHSD17B10KDM4E
SCHEMBL13428367 0.79 TERT (0.36) CYP2C9CYP1A2CYP3A4CYP2C19ALDH1A1
SCHEMBL13009170 0.79
SCHEMBL13428353 0.78 KMT2A (0.37) CYP1A2CYP3A4CYP2C19ALDH1A1KDM4E
SCHEMBL13008474 0.77 MAOA (0.40) ALDH1A1HPGDKDM4ELMNAMAPT
SCHEMBL13428337 0.77 HPGD (0.41) CYP2C9CYP1A2CYP3A4CYP2C19ALDH1A1
SCHEMBL13540613 0.74

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100051106-A1 Novel organic electroluminescent compounds and organic electroluminescent device using the same GRACEL DISPLAY INC. (KR) 2010-03-04 US disclosed
US-20100051106-A1 Novel organic electroluminescent compounds and organic electroluminescent device using the same GRACEL DISPLAY INC. (KR) 2010-03-04 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100051106-A1 Novel organic electroluminescent compounds and organic electroluminescent device using the same RPL36, RPL39, RPL36A P2RX4 2539/4885P2RX1 2098/4885P2RX3 2290/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.