SCHEMBL13428367

SCHEMBL13428367

CN1c2ccccc2N(c2cccc3c(-c4ccccc4)c4c(N5c6ccccc6N(C)c6ccccc65)cccc4c(-c4ccccc4)c23)c2ccccc21

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TERT O14746 2/20 0.36
ACHE P22303 2/20 0.35
LMNA P02545 3/20 0.35
KMT2A Q03164 3/20 0.35
SMN1; SMN2 Q16637 2/20 0.35
MAOA P21397 1/20 0.34
PDE6D O43924 1/20 0.33
GABRA1 P14867 1/20 0.33
GABRG2 P18507 1/20 0.33
GABRB3 P28472 1/20 0.33
GABRA5 P31644 1/20 0.33
CCKBR P32239 1/20 0.33
GABRA3 P34903 1/20 0.33
GABRA2 P47869 1/20 0.33
GABRB2 P47870 1/20 0.33
CYP1A2 P05177 2/20 0.33
CYP3A4 P08684 2/20 0.33
CYP2C9 P11712 2/20 0.33
CYP2C19 P33261 2/20 0.33
BRD4 O60885 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13009031 0.89 ACHE (0.35) TERTACHELMNAKMT2ASMN1; SMN2
SCHEMBL13540929 0.82
SCHEMBL13008476 0.80 POLB (0.42) TERTLMNAKMT2APDE6DCYP1A2
SCHEMBL13428353 0.80 KMT2A (0.37) ACHELMNAKMT2APDE6DCYP1A2
SCHEMBL13008474 0.79 MAOA (0.40) ACHELMNAKMT2AMAOAKDM4E
SCHEMBL13428351 0.79 P2RX4 (0.37) LMNAPDE6DCYP1A2CYP3A4CYP2C9
SCHEMBL13428337 0.79 HPGD (0.41) ACHELMNAKMT2ASMN1; SMN2PDE6D
SCHEMBL13296020 0.73 POLB (0.53) LMNAKMT2ASMN1; SMN2MAOACYP1A2
SCHEMBL13428370 0.71 ACHE (0.33) ACHEBRD4
SCHEMBL13428372 0.70 KMT2A (0.35) ACHELMNAKMT2ACYP1A2CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100051106-A1 Novel organic electroluminescent compounds and organic electroluminescent device using the same GRACEL DISPLAY INC. (KR) 2010-03-04 US disclosed
US-20100051106-A1 Novel organic electroluminescent compounds and organic electroluminescent device using the same GRACEL DISPLAY INC. (KR) 2010-03-04 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100051106-A1 Novel organic electroluminescent compounds and organic electroluminescent device using the same RPL36, RPL39, RPL36A TERT 323/4885ACHE 2982/4885LMNA 4186/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.