SCHEMBL13428371

SCHEMBL13428371

c1ccc(-c2c3ccccc3c(-c3ccccc3)c3c(N4c5ccccc5Sc5ccccc54)ccc(N4c5ccccc5Sc5ccccc54)c23)cc1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOA P21397 1/20 0.40
BCHE P06276 11/20 0.37
ACHE P22303 4/20 0.37
HTR2C P28335 2/20 0.36
DRD3 P35462 2/20 0.36
HTR2B P41595 2/20 0.36
HTR1A P08908 1/20 0.36
ADRB3 P13945 1/20 0.36
HTR2A P28223 1/20 0.36
HTR6 P50406 1/20 0.36
NOX1 Q9Y5S8 2/20 0.35
MEN1 O00255 2/20 0.35
KMT2A Q03164 2/20 0.35
ADRA2A P08913 1/20 0.35
ADRA2B P18089 1/20 0.35
ADRA2C P18825 1/20 0.35
CHRM3 P20309 1/20 0.35
SLC6A2 P23975 1/20 0.35
SLC6A4 P31645 1/20 0.35
L3MBTL1 Q9Y468 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13008474 0.90 MAOA (0.40) MAOABCHEACHEHTR2CDRD3
SCHEMBL13009031 0.79 ACHE (0.35) MAOAACHEMEN1KMT2AL3MBTL1
SCHEMBL14262591 0.77 BCHE (0.37) MAOABCHEACHEMEN1KMT2A
SCHEMBL13428385 0.77 P2RX4 (0.37) LMNA
SCHEMBL13428370 0.75 ACHE (0.33) ACHE
SCHEMBL13428372 0.74 KMT2A (0.35) ACHEMEN1KMT2ASLC6A2SLC6A4
SCHEMBL13427118 0.74 HDAC6 (0.42) MAOABCHEACHEHTR2CDRD3
SCHEMBL13009399 0.74 HDAC6 (0.42) MAOABCHEACHEHTR2CDRD3
SCHEMBL1103441 0.74 TLR7 (0.34) MAOALMNA
SCHEMBL13428343 0.73 BCHE (0.42) MAOABCHEACHEHTR2CHTR2B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100051106-A1 Novel organic electroluminescent compounds and organic electroluminescent device using the same GRACEL DISPLAY INC. (KR) 2010-03-04 US disclosed
US-20100051106-A1 Novel organic electroluminescent compounds and organic electroluminescent device using the same GRACEL DISPLAY INC. (KR) 2010-03-04 US disclosed
EP-2141214-A2 Novel organic electroluminescent compounds and organic electroluminescent device using the same Gracel Display Inc. (KR) 2010-01-06 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100051106-A1 Novel organic electroluminescent compounds and organic electroluminescent device using the same RPL36, RPL39, RPL36A MAOA 1343/4885BCHE 3337/4885ACHE 2982/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.