Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.38 |
| ▸ | ABL1 | P00519 | 1/20 | 0.37 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.37 |
| ▸ | GRIN2D | O15399 | 3/20 | 0.35 |
| ▸ | GRIN3B | O60391 | 3/20 | 0.35 |
| ▸ | GRIN1 | Q05586 | 3/20 | 0.35 |
| ▸ | GRIN2A | Q12879 | 3/20 | 0.35 |
| ▸ | GRIN2B | Q13224 | 3/20 | 0.35 |
| ▸ | GRIN2C | Q14957 | 3/20 | 0.35 |
| ▸ | GRIN3A | Q8TCU5 | 3/20 | 0.35 |
| ▸ | SLC22A2 | O15244 | 2/20 | 0.33 |
| ▸ | SLC47A1 | Q96FL8 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | STAT6 | P42226 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | BLM | P54132 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL985712 | 0.78 | ABL1 (0.39) | SIGMAR1ABL1RIN1GRIN2DGRIN3B | |
| SCHEMBL985709 | 0.78 | ABL1 (0.39) | SIGMAR1ABL1RIN1GRIN2DGRIN3B | |
| SCHEMBL985710 | 0.78 | ABL1 (0.39) | SIGMAR1ABL1RIN1GRIN2DGRIN3B | |
| SCHEMBL4394773 | 0.69 | SIGMAR1 (0.41) | SIGMAR1GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL2915914 | 0.67 | GRIN2D (0.42) | SIGMAR1GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL31254406 | 0.67 | SIGMAR1 (0.42) | SIGMAR1GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL3076057 | 0.67 | SIGMAR1 (0.41) | SIGMAR1ABL1RIN1GRIN2DGRIN3B | |
| SCHEMBL17337972 | 0.67 | THRB (0.45) | SIGMAR1ABL1RIN1TSHRTHRB | |
| SCHEMBL17337971 | 0.67 | THRB (0.45) | SIGMAR1ABL1RIN1TSHRTHRB | |
| SCHEMBL17338027 | 0.66 | THRB (0.44) | SIGMAR1ABL1RIN1TSHRTHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2099749-B1 | C-H BOND AMINATION AND OLEFIN AZIRIDINATION WITH BETA-DIKETIMINATO COPPER CATALYSTS | UNIV GEORGETOWN (US) | 2015-09-23 | — | — | EP | disclosed |
| US-8471051-B2 | C-H bond amination and olefin aziridination with β-diketiminato copper catalysts | GEORGETOWN UNIVERSITY (US) | 2013-06-25 | — | — | US | disclosed |
| US-8471051-B2 | C-H bond amination and olefin aziridination with β-diketiminato copper catalysts | GEORGETOWN UNIVERSITY (US) | 2013-06-25 | — | — | US | disclosed |
| US-20100056806-A1 | C-H Bond Amination and Olefin Aziridination with Beta-Diketiminato Copper Catalysts | GEORGETOWN UNIVERSITY (US) | 2010-03-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100056806-A1 | C-H Bond Amination and Olefin Aziridination with Beta-Diketiminato Copper Catalysts | AOC2, AOC1, AOC3 | SIGMAR1 556/4885ABL1 325/4885RIN1 2986/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.