SCHEMBL13429618

SCHEMBL13429618

CO[Si](OC)(OC)c1ccc(-c2cc(Br)c(Br)c(Br)c2)cc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
APEX1 P27695 1/20 0.46
CA2 P00918 2/20 0.36
CA4 P22748 1/20 0.36
CRHBP P24387 1/20 0.31
CRHR2 Q13324 1/20 0.31
MAPT P10636 2/20 0.31
NQO2 P16083 1/20 0.31
CA12 O43570 1/20 0.31
CA1 P00915 1/20 0.31
CA9 Q16790 1/20 0.31
KDM4E B2RXH2 1/20 0.31
MEN1 O00255 1/20 0.31
NPC1 O15118 1/20 0.31
ALDH1A1 P00352 1/20 0.31
HPGD P15428 1/20 0.31
MAPK1 P28482 1/20 0.31
RAB9A P51151 1/20 0.31
KMT2A Q03164 1/20 0.31
NPSR1 Q6W5P4 1/20 0.31
PLK4 O00444 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16154616 0.83 ABL1 (0.38) CA2CA12CA1CA9NPC1
SCHEMBL13429719 0.82 IDO1 (0.33) NPC1MAPK1RAB9A
SCHEMBL3353844 0.81 ESR2 (0.33) NPC1MAPK1RAB9ADYRK1ACLK4
SCHEMBL13429624 0.79 ALDH1A1 (0.42) CA2MAPTCA12CA9KDM4E
SCHEMBL13429605 0.79 CA2 (0.44) APEX1CA2CA4MAPTNQO2
SCHEMBL13429619 0.78 ALDH1A1 (0.36) MAPTNQO2KDM4EMEN1NPC1
SCHEMBL13429632 0.75 APP (0.32)
SCHEMBL15734438 0.74 ABCB1 (0.36) MAP4K4
SCHEMBL13429623 0.74 GABRG2 (0.49) MAPTKDM4EMEN1NPC1ALDH1A1
SCHEMBL50828 0.73 KDM4E (0.32) CA2CA12CA1CA9KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100069603-A1 METHOD FOR PRODUCING STRUCTURE WHEREIN AROMATIC POLYMER IS BONDED TO BASE, STRUCTURE HAVING AROMATIC POLYMER CHAIN BONDED TO CONDUCTIVE BASE, AND ELECTRONIC DEVICE COMPRISING THE STRUCTURE SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2010-03-18 US disclosed