Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 2/20 | 0.44 |
| ▸ | LPL | P06858 | 12/20 | 0.36 |
| ▸ | LIPG | Q9Y5X9 | 12/20 | 0.36 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.33 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 2/20 | 0.32 |
| ▸ | CA2 | P00918 | 2/20 | 0.32 |
| ▸ | CA9 | Q16790 | 2/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA3 | P07451 | 1/20 | 0.32 |
| ▸ | CA4 | P22748 | 1/20 | 0.32 |
| ▸ | CA6 | P23280 | 1/20 | 0.32 |
| ▸ | CA5A | P35218 | 1/20 | 0.32 |
| ▸ | CA7 | P43166 | 1/20 | 0.32 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.32 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20068614 | 0.80 | DGAT1 (0.56) | DGAT1LPLLIPGFFAR1CA1 | |
| SCHEMBL3220509 | 0.80 | DGAT1 (0.44) | DGAT1LPLLIPGFFAR1IRAK4 | |
| SCHEMBL2147791 | 0.77 | DGAT1 (0.44) | DGAT1LPLLIPGFFAR1IRAK4 | |
| SCHEMBL29406802 | 0.77 | DGAT1 (0.44) | DGAT1LPLLIPGFFAR1IRAK4 | |
| SCHEMBL21125909 | 0.76 | DGAT1 (0.67) | DGAT1LPLLIPGCA1CA2 | |
| SCHEMBL13430064 | 0.75 | DGAT1 (0.44) | DGAT1LPLLIPGFFAR1IRAK4 | |
| SCHEMBL2148136 | 0.74 | DGAT1 (0.46) | DGAT1LPLLIPGFFAR1IRAK4 | |
| SCHEMBL13429886 | 0.74 | DGAT1 (0.46) | DGAT1LPLLIPGFFAR1IRAK4 | |
| SCHEMBL18573099 | 0.72 | DGAT1 (0.60) | DGAT1LPLLIPGCA1CA2 | |
| SCHEMBL15747741 | 0.72 | DGAT1 (0.50) | DGAT1LPLLIPGFFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100069441-A1 | ANTIMICROBIAL INDOLINE COMPOUNDS FOR TREATMENT OF BACTERIAL INFECTIONS | GORDEEV MIKHAIL FEDOROVICH | 2010-03-18 | — | — | US | disclosed |
| US-20100069441-A1 | ANTIMICROBIAL INDOLINE COMPOUNDS FOR TREATMENT OF BACTERIAL INFECTIONS | GORDEEV MIKHAIL FEDOROVICH | 2010-03-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100069441-A1 | ANTIMICROBIAL INDOLINE COMPOUNDS FOR TREATMENT OF BACTERIAL INFECTIONS | IDO1, IDO2, INMT | DGAT1 3118/4885LPL 4201/4885LIPG 3592/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.