SCHEMBL29406802

SCHEMBL29406802

Cn1nnc(-c2ccc(B3OC(C)(C)C(C)(C)O3)cn2)n1

nearest known ligand 0.44

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
DGAT1 O75907 2/20 0.44
LPL P06858 10/20 0.38
LIPG Q9Y5X9 10/20 0.38
PPARA Q07869 1/20 0.34
MAOA P21397 1/20 0.34
MAOB P27338 1/20 0.34
FFAR1 O14842 1/20 0.32
IRAK4 Q9NWZ3 1/20 0.32
USP30 Q70CQ3 1/20 0.31
CA1 P00915 1/20 0.31
CA2 P00918 1/20 0.31
CA9 Q16790 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2147791 1.00 DGAT1 (0.44) DGAT1LPLLIPGPPARAMAOA
SCHEMBL22238944 0.84 MAOA (0.34) DGAT1PPARAMAOAMAOB
SCHEMBL13429939 0.80 DGAT1 (0.44) DGAT1LPLLIPGFFAR1
SCHEMBL3233070 0.80 LPL (0.53) LPLLIPGPPARACA1CA2
SCHEMBL12461124 0.80 DGAT1 (0.44) DGAT1LPLLIPGPPARAFFAR1
SCHEMBL13456682 0.79 DGAT1 (0.43) DGAT1LPLLIPG
SCHEMBL13429886 0.79 DGAT1 (0.46) DGAT1LPLLIPGFFAR1IRAK4
SCHEMBL20068614 0.79 DGAT1 (0.56) DGAT1LPLLIPGFFAR1CA1
SCHEMBL3220509 0.78 DGAT1 (0.44) DGAT1LPLLIPGFFAR1IRAK4
SCHEMBL13429960 0.77 DGAT1 (0.44) DGAT1LPLLIPGFFAR1IRAK4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114933596-B Preparation method of tedizolid 河北广祥制药有限公司 2023-09-05 CN claimed
CN-115792047-A Method for detecting tedizolid phosphate intermediate related substances 四川美域高生物医药科技有限公司 2023-03-14 CN claimed
CN-114933596-A Preparation method of tedizolid 河北广祥制药有限公司 2022-08-23 CN claimed
CN-114933596-B Preparation method of tedizolid 河北广祥制药有限公司 2023-09-05 CN disclosed
CN-116031394-A Method for coating ferroelectric polymer interface layer with metallic zinc and application thereof 兰州大学 2023-04-28 CN disclosed
CN-113214239-B Tedizolid refining process and preparation method of tedizole phosphate 海南通用康力制药有限公司 2023-04-07 CN disclosed
CN-115792047-A Method for detecting tedizolid phosphate intermediate related substances 四川美域高生物医药科技有限公司 2023-03-14 CN disclosed
CN-114933596-A Preparation method of tedizolid 河北广祥制药有限公司 2022-08-23 CN disclosed
WO-2022166022-A1 PURIFICATION METHOD FOR TEDIZOLID PHOSPHATE 海南通用康力制药有限公司 2022-08-11 WO disclosed
CN-114105968-A Method for removing palladium residue of tedizolid 河北明吉化工科技有限公司 2022-03-01 CN disclosed