Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 6/20 | 0.48 |
| ▸ | PTGS1 | P23219 | 5/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | NT5E | P21589 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 7/20 | 0.39 |
| ▸ | CA1 | P00915 | 7/20 | 0.39 |
| ▸ | CA2 | P00918 | 7/20 | 0.39 |
| ▸ | CA9 | Q16790 | 7/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.37 |
| ▸ | LOX | P28300 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.36 |
| ▸ | RELA | Q04206 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10772646 | 0.75 | XDH (0.64) | PTGS2PTGS1KDM4EXDH | |
| SCHEMBL10772634 | 0.75 | RIPK2 (0.55) | ALDH1A1KDM4ERAB9ARIPK2SMN1; SMN2 | |
| SCHEMBL13430490 | 0.72 | XDH (0.41) | ALDH1A1PKMRAB9ARIPK2SMN1; SMN2 | |
| SCHEMBL23718278 | 0.72 | ALDH1A1 (0.75) | ALDH1A1TSHRRAB9ASMN1; SMN2NPC1 | |
| SCHEMBL5408685 | 0.71 | PTGS2 (0.51) | PTGS2PTGS1CA12CA1CA2 | |
| SCHEMBL5408682 | 0.71 | PTGS2 (0.51) | PTGS2PTGS1CA12CA1CA2 | |
| SCHEMBL15316250 | 0.71 | PTGS2 (0.46) | PTGS2PTGS1ALDH1A1PKMTSHR | |
| SCHEMBL6250200 | 0.70 | POLB (0.55) | ALDH1A1TSHRNT5EKDM4ECA12 | |
| SCHEMBL1245336 | 0.70 | KMT2A (0.62) | PTGS2PTGS1KDM4EXDH | |
| SCHEMBL5021191 | 0.68 | CCR1 (0.47) | PTGS2PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100063262-A1 | PROCESS FOR PRODUCING 5-AMINOPYRAZOLE DERIVATIVE, AND AZO DYE | FUJIFILM CORPORATION (JP) | 2010-03-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100063262-A1 | PROCESS FOR PRODUCING 5-AMINOPYRAZOLE DERIVATIVE, AND AZO DYE | H1-5, CYP3A5, IL5 | PTGS2 674/4885PTGS1 804/4885ALDH1A1 134/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.