Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 9/20 | 0.51 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.51 |
| ▸ | PTGS1 | P23219 | 6/20 | 0.44 |
| ▸ | CA12 | O43570 | 5/20 | 0.44 |
| ▸ | CA1 | P00915 | 5/20 | 0.44 |
| ▸ | CA2 | P00918 | 5/20 | 0.44 |
| ▸ | CA9 | Q16790 | 5/20 | 0.44 |
| ▸ | LOX | P28300 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.40 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.40 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.40 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.40 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5408682 | 1.00 | PTGS2 (0.51) | PTGS2ALOX5PTGS1CA12CA1 | |
| SCHEMBL5410340 | 0.85 | PTPN11 (0.48) | PTGS2ALOX5PTGS1CA12CA1 | |
| SCHEMBL5410341 | 0.85 | PTPN11 (0.48) | PTGS2ALOX5PTGS1CA12CA1 | |
| SCHEMBL12126424 | 0.80 | RPS6KA3 (0.48) | PTGS2ALOX5CA12CA2CA9 | |
| SCHEMBL29805379 | 0.79 | RPS6KA3 (0.47) | PTGS2ALOX5CA12CA2CA9 | |
| SCHEMBL12854629 | 0.74 | POLB (0.55) | PTGS2ALOX5PTGS1CA12CA1 | |
| SCHEMBL4070857 | 0.74 | POLB (0.55) | PTGS2ALOX5PTGS1CA12CA1 | |
| SCHEMBL5273697 | 0.73 | RAB9A (0.49) | PTGS2PTGS1CA12CA1CA2 | |
| Sulfuric Acid SCHEMBL5422236 | 0.72 | RAB9A (0.48) | PTGS2ALOX5PTGS1CA12CA1 | |
| SCHEMBL13430482 | 0.71 | PTGS2 (0.48) | PTGS2PTGS1CA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7195649-B2 | N-aryl-4,5-diaminopyrazoles and dyes containing said compounds | WELLA AG (DE) | 2007-03-27 | — | — | US | disclosed |
| EP-1562540-A1 | N-ARYL-4,5-DIAMINOPYRAZOLS AND DYES CONTAINING SAID COMPOUNDS | Wella Aktiengesellschaft (DE) | 2005-08-17 | — | — | EP | disclosed |
| US-20050081312-A1 | N-aryl-4,5-diaminopyrazoles and dyes containing said compounds | HFC PRESTIGE INTERNATIONAL OPERATIONS SWITZERLAND SÀRL (CH) | 2005-04-21 | — | — | US | disclosed |
| WO-2004047781-A1 | N-ARYL-4,5-DIAMINOPYRAZOLS AND DYES CONTAINING SAID COMPOUNDS | WELLA AKTIENGESELLSCHAFT (DE) | 2004-06-10 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050081312-A1 | N-aryl-4,5-diaminopyrazoles and dyes containing said compounds | KRT18, F12, HCN3 | PTGS2 4414/4885ALOX5 2995/4885PTGS1 4031/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.