Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.47 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | PTGES | O14684 | 1/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.41 |
| ▸ | ESR1 | P03372 | 1/20 | 0.41 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3797212 | 0.79 | SMN1; SMN2 (0.49) | ALDH1A1MAPK14MEN1KMT2AHPGD | |
| SCHEMBL6430222 | 0.78 | MEN1 (0.63) | ALDH1A1MAPK14MEN1KMT2AHTT | |
| SCHEMBL27605169 | 0.78 | ALDH1A1 (0.44) | ALDH1A1MAPK14SMN1; SMN2NPC1RAB9A | |
| SCHEMBL15708137 | 0.76 | ALDH1A1 (0.47) | ALDH1A1MAPK14MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL9547593 | 0.76 | ALDH1A1 (0.51) | ALDH1A1MAPK14HPGDSMN1; SMN2NPC1 | |
| SCHEMBL3239999 | 0.75 | OXTR (0.48) | ALDH1A1MAPK14MEN1KMT2AHTT | |
| SCHEMBL14427603 | 0.73 | MEN1 (0.66) | ALDH1A1MEN1KMT2AHTTHPGD | |
| SCHEMBL3425918 | 0.72 | GLI1 (0.55) | ALDH1A1MAPK14MEN1KMT2AHTT | |
| SCHEMBL1006444 | 0.71 | HTT (0.71) | ALDH1A1MEN1KMT2AHTTHPGD | |
| SCHEMBL4838671 | 0.71 | ALDH1A1 (0.41) | ALDH1A1MAPK14MEN1KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010038252-A2 | CARBONYL DERIVATIVES HAVING A C3 SYMMETRY, THEIR PREPARATION AND USES THEREOF | UNIVERSITÀ DEGLI STUDI DI ROMA LA SAPIENZA (IT) | 2010-04-08 | — | — | WO | disclosed |