SCHEMBL9547593

SCHEMBL9547593

CCN(CC)C(=O)N(CC)c1ccc2ccccc2c1

nearest known ligand 0.51

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.51
TSHR P16473 2/20 0.51
GLA P06280 1/20 0.51
LMNA P02545 2/20 0.44
OXTR P30559 1/20 0.43
ABCC1 P33527 1/20 0.41
MAPK14 Q16539 1/20 0.40
RAB9A P51151 2/20 0.40
POLB P06746 1/20 0.40
HSD17B10 Q99714 1/20 0.40
KDM4E B2RXH2 1/20 0.40
HPGD P15428 1/20 0.40
NPC1 O15118 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3797212 0.83 SMN1; SMN2 (0.49) ALDH1A1TSHRGLAOXTRMAPK14
SCHEMBL27605169 0.82 ALDH1A1 (0.44) ALDH1A1TSHRGLAOXTRMAPK14
SCHEMBL15708137 0.81 ALDH1A1 (0.47) ALDH1A1TSHRGLALMNAOXTR
SCHEMBL3239999 0.79 OXTR (0.48) ALDH1A1TSHRGLALMNAOXTR
SCHEMBL11279390 0.79 ALDH1A1 (0.81) ALDH1A1TSHRGLALMNAHPGD
SCHEMBL13430558 0.76 ALDH1A1 (0.47) ALDH1A1TSHRGLAMAPK14RAB9A
SCHEMBL4838671 0.75 ALDH1A1 (0.41) ALDH1A1TSHRGLAOXTRMAPK14
SCHEMBL14052528 0.71 HPGD (0.64) ALDH1A1LMNARAB9AHPGDNPC1
SCHEMBL10360408 0.71 CYP2A6 (0.48)
SCHEMBL9547516 0.71 NPSR1 (0.54) ALDH1A1TSHRLMNARAB9AHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5194660-A Processes for producing carbamates and isocyanates UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION (US) 1993-03-16 US disclosed
EP-0083096-B1 PRODUCTION OF URETHANE COMPOUNDS Asahi Kasei Kogyo Kabushiki Kaisha (JP) 1987-02-25 EP disclosed
US-4621149-A PLATINUM GROUP METAL HALOGEN OR HALOGEN COMPOUND ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) 1986-11-04 US disclosed