Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OXTR | P30559 | 1/20 | 0.48 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.45 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3797212 | 0.82 | SMN1; SMN2 (0.49) | OXTRMTNR1AMTNR1BRAB9AALDH1A1 | |
| SCHEMBL27605169 | 0.81 | ALDH1A1 (0.44) | OXTRRAB9AALDH1A1GLATSHR | |
| SCHEMBL17102369 | 0.80 | MTNR1B (0.63) | MTNR1AMTNR1B | |
| SCHEMBL7653262 | 0.80 | ALDH1A1 (0.66) | HTTALDH1A1GLATSHRSMN1; SMN2 | |
| SCHEMBL9547593 | 0.79 | ALDH1A1 (0.51) | OXTRRAB9AALDH1A1GLATSHR | |
| SCHEMBL15708137 | 0.79 | ALDH1A1 (0.47) | OXTRRAB9AALDH1A1GLATSHR | |
| SCHEMBL2097822 | 0.79 | LMNA (0.45) | MTNR1AMTNR1BHTTRAB9AALDH1A1 | |
| Hydrochloric Acid SCHEMBL27718102 | 0.78 | ALDH1A1 (0.63) | HTTALDH1A1GLATSHRSMN1; SMN2 | |
| SCHEMBL28129412 | 0.78 | MTNR1A (0.52) | MTNR1AMTNR1B | |
| SCHEMBL5454456 | 0.77 | HTT (0.51) | HTTRAB9AALDH1A1TSHRSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010022355-A1 | COMPOUNDS AND METHODS FOR TREATING RESPIRATORY DISEASES | PURDUE RESEARCH FOUNDATION (US) | 2010-02-25 | — | — | WO | disclosed |