Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 3/20 | 0.49 |
| ▸ | HTR7 | P34969 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.39 |
| ▸ | GPR3 | P46089 | 1/20 | 0.36 |
| ▸ | RORC | P51449 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.36 |
| ▸ | SCN9A | Q15858 | 5/20 | 0.35 |
| ▸ | IDO1 | P14902 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13430732 | 0.86 | KCNH2 (0.48) | KCNH2HTR7ALDH1A1KDM4ENR4A2 | |
| SCHEMBL13430733 | 0.83 | KCNH2 (0.46) | KCNH2HTR7ALDH1A1KDM4ENR4A2 | |
| SCHEMBL12260366 | 0.81 | KCNH2 (0.42) | KCNH2ALDH1A1KDM4ENR4A2RORC | |
| SCHEMBL13430740 | 0.79 | KDM4E (0.43) | KCNH2HTR7ALDH1A1KDM4ENR4A2 | |
| SCHEMBL29291154 | 0.77 | HSP90AA1 (0.44) | KCNH2 | |
| SCHEMBL65417 | 0.77 | HTR7 (0.44) | HTR7ALDH1A1KDM4ENR4A2GPR3 | |
| SCHEMBL28534559 | 0.76 | KCNH2 (0.50) | KCNH2HTR7ALDH1A1KDM4ENR4A2 | |
| SCHEMBL29445759 | 0.75 | KCNH2 (0.38) | KCNH2HTR7ALDH1A1KDM4ERORC | |
| SCHEMBL13335134 | 0.75 | NR4A2 (0.44) | KCNH2HTR7ALDH1A1KDM4ENR4A2 | |
| SCHEMBL18976935 | 0.75 | ATP4A (0.50) | HTR7ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8337999-B2 | Organic electroluminescent device including at least one layer containing an indole derivative | UDC IRELAND LIMITED (IE) | 2012-12-25 | — | — | US | disclosed |
| US-8337999-B2 | Organic electroluminescent device including at least one layer containing an indole derivative | UDC IRELAND LIMITED (IE) | 2012-12-25 | — | — | US | disclosed |
| US-20100060151-A1 | ORGANIC ELECTROLUMINESCENT DEVICE AND INDOLE DERIVATIVE | FUJIFILM CORPORATION (JP) | 2010-03-11 | — | — | US | disclosed |
| US-20100060151-A1 | ORGANIC ELECTROLUMINESCENT DEVICE AND INDOLE DERIVATIVE | FUJIFILM CORPORATION (JP) | 2010-03-11 | — | — | US | disclosed |
| US-20100026174-A1 | ORGANIC ELECTROLUMINESCENT DEVICE | FUJIFILM CORPORATION (JP) | 2010-02-04 | — | — | US | disclosed |
| US-20100026174-A1 | ORGANIC ELECTROLUMINESCENT DEVICE | FUJIFILM CORPORATION (JP) | 2010-02-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100060151-A1 | ORGANIC ELECTROLUMINESCENT DEVICE AND INDOLE DERIVATIVE | IDO1, CHRM1, L1CAM | KCNH2 52/4885HTR7 674/4885ALDH1A1 64/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.