SCHEMBL13433009

SCHEMBL13433009

c1ccc(-c2ccc(-c3ccc4c(c3)c3ccccc3n4-c3cccc4c(-c5c6ccccc6c(-c6ccccc6)c6ccccc56)cccc34)cc2)cc1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSPO P30536 5/20 0.38
ALDH1A1 P00352 1/20 0.37
ATM Q13315 2/20 0.34
L3MBTL1 Q9Y468 2/20 0.34
KDM4E B2RXH2 1/20 0.34
KMT2A Q03164 2/20 0.33
DNM1 Q05193 1/20 0.33
EDNRB P24530 1/20 0.32
EDNRA P25101 1/20 0.32
NPY5R Q15761 1/20 0.32
MAPK14 Q16539 1/20 0.32
TYMS P04818 1/20 0.31
THRB P10828 2/20 0.30
THRA P10827 1/20 0.30
NR4A2 P43354 2/20 0.30
MEN1 O00255 1/20 0.30
APAF1 O14727 1/20 0.30
NPC1 O15118 1/20 0.30
LMNA P02545 1/20 0.30
MAPT P10636 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13433194 0.99 TSPO (0.38) TSPOALDH1A1ATML3MBTL1KDM4E
SCHEMBL262437 0.94 L3MBTL1 (0.45) TSPOALDH1A1ATML3MBTL1KDM4E
SCHEMBL13433188 0.93 TSPO (0.38) TSPOALDH1A1ATML3MBTL1KDM4E
SCHEMBL13433007 0.93 TSPO (0.39) TSPOALDH1A1ATML3MBTL1KDM4E
SCHEMBL13433170 0.92 TSPO (0.38) TSPOALDH1A1ATML3MBTL1KDM4E
SCHEMBL13433084 0.92 TSPO (0.40) TSPOALDH1A1ATML3MBTL1KDM4E
SCHEMBL262611 0.92 TSPO (0.38) TSPOALDH1A1DNM1NPY5R
SCHEMBL13432963 0.91 AKT1 (0.37) TSPOALDH1A1
SCHEMBL25658208 0.90 L3MBTL1 (0.42) TSPOALDH1A1ATML3MBTL1KDM4E
SCHEMBL7603781 0.90 ALDH1A1 (0.44) ALDH1A1ATML3MBTL1KDM4EKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100069647-A1 Carbazole Derivative, Light-Emitting Element Material, Light-Emitting Element, and Light-Emitting Device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. 2010-03-18 US disclosed
US-20100069647-A1 Carbazole Derivative, Light-Emitting Element Material, Light-Emitting Element, and Light-Emitting Device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. 2010-03-18 US disclosed
WO-2010005066-A1 CARBAZOLE DERIVATIVE, LIGHT-EMITTING ELEMENT MATERIAL, LIGHT-EMITTING ELEMENT, AND LIGHT-EMITTING DEVICE SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2010-01-14 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100069647-A1 Carbazole Derivative, Light-Emitting Element Material, Light-Emitting Element, and Light-Emitting Device CRY1, CHRM1, CYP1A1 TSPO 3180/4885ALDH1A1 16/4885ATM 2629/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.