Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.53 |
| ▸ | RRM1 | P23921 | 1/20 | 0.53 |
| ▸ | NOD1 | Q9Y239 | 5/20 | 0.51 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.50 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.50 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.50 |
| ▸ | GRIK1 | P39086 | 2/20 | 0.47 |
| ▸ | GRIK2 | Q13002 | 2/20 | 0.47 |
| ▸ | EPHX1 | P07099 | 6/20 | 0.46 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.45 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.45 |
| ▸ | S1PR2 | O95136 | 2/20 | 0.43 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.43 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.43 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.43 |
| ▸ | FNTA | P49354 | 1/20 | 0.43 |
| ▸ | FNTB | P49356 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21111056 | 0.92 | DPP7 (0.58) | DPP7RRM1NOD1GNAI3GNAO1 | |
| SCHEMBL29551297 | 0.89 | DPP7 (0.54) | DPP7RRM1NOD1GNAI3GNAO1 | |
| SCHEMBL8730134 | 0.87 | NOD1 (0.52) | DPP7RRM1NOD1GNAI3GNAO1 | |
| SCHEMBL1344672 | 0.87 | SLC1A2 (0.42) | DPP7NOD1GRIK1GRIK2SLC1A2 | |
| SCHEMBL3508097 | 0.84 | OTC (0.50) | DPP7RRM1NOD1GNAI3GNAO1 | |
| SCHEMBL1004634 | 0.84 | OTC (0.50) | DPP7RRM1NOD1GNAI3GNAO1 | |
| SCHEMBL30302208 | 0.83 | DPP7 (0.46) | DPP7NOD1GNAI3GNAO1GNAI1 | |
| SCHEMBL30286002 | 0.83 | DPP7 (0.46) | DPP7NOD1GNAI3GNAO1GNAI1 | |
| Hydrochloric Acid SCHEMBL30271216 | 0.83 | OTC (0.49) | DPP7NOD1GNAI3GNAO1GNAI1 | |
| SCHEMBL2863618 | 0.81 | EPHX1 (0.63) | DPP7RRM1NOD1GNAI3GNAO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1828109-B1 | GUANIDINE DERIVATIVES AS INHIBITORS OF DDAH | UCL BUSINESS PLC (GB) | 2013-06-05 | — | — | EP | disclosed |
| US-8063104-B2 | Guanidine derivatives as inhibitors of DDAH | UCL BUSINESS PLC (GB) | 2011-11-22 | — | — | US | disclosed |
| US-20090069331-A1 | GUANIDINE DERIVATIVES AS INHIBITORS OF DDAH | UCL Biomedica PLC c/o Finance Division University College of London (GB) | 2009-03-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090069331-A1 | GUANIDINE DERIVATIVES AS INHIBITORS OF DDAH | DDAH1, DOHH, IMPDH1 | DPP7 560/4885RRM1 1281/4885NOD1 2690/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.