Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 1/20 | 0.69 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | TPI1 | P60174 | 1/20 | 0.33 |
| ▸ | SPHK2 | Q9NRA0 | 1/20 | 0.32 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1343831 | 1.00 | CYP2D6 (0.69) | CYP2D6TSHRTPI1SPHK2SPHK1 | |
| SCHEMBL12127653 | 1.00 | CYP2D6 (0.69) | CYP2D6TSHRTPI1SPHK2SPHK1 | |
| SCHEMBL12757722 | 1.00 | CYP2D6 (0.69) | CYP2D6TSHRTPI1SPHK2SPHK1 | |
| SCHEMBL12757720 | 0.97 | CYP2D6 (0.73) | CYP2D6TSHRTPI1 | |
| SCHEMBL12129809 | 0.97 | CYP2D6 (0.73) | CYP2D6TSHRTPI1 | |
| SCHEMBL1341624 | 0.97 | CYP2D6 (0.73) | CYP2D6TSHRTPI1 | |
| SCHEMBL12127650 | 0.97 | CYP2D6 (0.73) | CYP2D6TSHRTPI1 | |
| SCHEMBL19698072 | 0.90 | CYP2D6 (0.73) | CYP2D6TSHRTPI1 | |
| SCHEMBL15174081 | 0.87 | CYP2D6 (0.52) | CYP2D6TSHRSPHK2SPHK1 | |
| SCHEMBL15174509 | 0.87 | CYP2D6 (0.52) | CYP2D6TSHRSPHK2SPHK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8802609-B2 | Nitrile and amidoxime compounds and methods of preparation for semiconductor processing | EKC TECHNOLOGY INC | 2014-08-12 | — | — | US | claimed |
| US-20130035272-A1 | NOVEL NITRILE AND AMIDOXIME COMPOUNDS AND METHODS OF PREPARATION FOR SEMICONDUCTOR PROCESSING | EKC TECHNOLOGY INC. | 2013-02-07 | — | — | US | claimed |
| US-8062429-B2 | Methods of cleaning semiconductor devices at the back end of line using amidoxime compositions | EKC TECHNOLOGY, INC. (US) | 2011-11-22 | — | — | US | claimed |
| US-20110065622-A1 | NOVEL NITRILE AND AMIDOXIME COMPOUNDS AND METHODS OF PREPARATION FOR SEMICONDUCTOR PROCESSING | EKC TECHNOLOGY, INC. | 2011-03-17 | — | — | US | claimed |
| EP-2207750-A1 | STABILIZATION OF HYDROXYLAMINE CONTAINING SOLUTIONS AND METHOD FOR THEIR PREPARATION | EKC Technology, INC. (US) | 2010-07-21 | — | — | EP | claimed |
| US-20100043823-A1 | METHODS OF CLEANING SEMICONDUCTOR DEVICES AT THE BACK END OF LINE USING AMIDOXIME COMOSITIONS | U.S. BANK TRUST COMPANY, NATIONAL ASSOCIATION, AS NOTES COLLATERAL AGENT | 2010-02-25 | — | — | US | claimed |
| US-20090130849-A1 | CHEMICAL MECHANICAL POLISHING AND WAFER CLEANING COMPOSITION COMPRISING AMIDOXIME COMPOUNDS AND ASSOCIATED METHOD FOR USE | EKC TECHNOLOGY, INC. | 2009-05-21 | — | — | US | claimed |
| WO-2009058274-A1 | CHEMICAL MECHANICAL POLISHING AND WAFER CLEANING COMPOSITION COMPRISING AMIDOXIME COMPOUNDS AND ASSOCIATED METHOD FOR USE | EKC TECHNOLOGY, INC. (US) | 2009-05-07 | — | — | WO | claimed |
| WO-2009058278-A1 | METHODS OF CLEANING SEMICONDUCTOR DEVICES AT THE BACK END OF LINE USING AMIDOXIME COMPOSITIONS | EKC TECHNOLOGY, INC (US) | 2009-05-07 | — | — | WO | claimed |
| WO-2009058273-A1 | STABILIZATION OF HYDROXYLAMINE CONTAINING SOLUTIONS AND METHOD FOR THEIR PREPARATION | EKC TECHNOLOGY, INC. (US) | 2009-05-07 | — | — | WO | claimed |
| US-20090112024-A1 | STABILIZATION OF HYDROXYLAMINE CONTAINING SOLUTIONS AND METHOD FOR THEIR PREPARATION | EKC TECHNOLOGY, INC. | 2009-04-30 | — | — | US | claimed |
| US-20090111965-A1 | NOVEL NITRILE AND AMIDOXIME COMPOUNDS AND METHODS OF PREPARATION | EKC TECHNOLOGY, INC. | 2009-04-30 | — | — | US | claimed |
| US-8802609-B2 | Nitrile and amidoxime compounds and methods of preparation for semiconductor processing | EKC TECHNOLOGY INC | 2014-08-12 | — | — | US | disclosed |
| EP-2207872-B1 | NOVEL NITRILE AND AMIDOXIME COMPOUNDS AND METHODS OF PREPARATION | EKC TECHNOLOGY INC (US) | 2013-07-03 | — | — | EP | disclosed |
| US-20130035272-A1 | NOVEL NITRILE AND AMIDOXIME COMPOUNDS AND METHODS OF PREPARATION FOR SEMICONDUCTOR PROCESSING | EKC TECHNOLOGY INC. | 2013-02-07 | — | — | US | disclosed |
| US-8062429-B2 | Methods of cleaning semiconductor devices at the back end of line using amidoxime compositions | EKC TECHNOLOGY, INC. (US) | 2011-11-22 | — | — | US | disclosed |
| WO-2009058274-A1 | CHEMICAL MECHANICAL POLISHING AND WAFER CLEANING COMPOSITION COMPRISING AMIDOXIME COMPOUNDS AND ASSOCIATED METHOD FOR USE | EKC TECHNOLOGY, INC. (US) | 2009-05-07 | — | — | WO | disclosed |
| WO-2009058278-A1 | METHODS OF CLEANING SEMICONDUCTOR DEVICES AT THE BACK END OF LINE USING AMIDOXIME COMPOSITIONS | EKC TECHNOLOGY, INC (US) | 2009-05-07 | — | — | WO | disclosed |
| US-20090112024-A1 | STABILIZATION OF HYDROXYLAMINE CONTAINING SOLUTIONS AND METHOD FOR THEIR PREPARATION | EKC TECHNOLOGY, INC. | 2009-04-30 | — | — | US | disclosed |
| US-20090111965-A1 | NOVEL NITRILE AND AMIDOXIME COMPOUNDS AND METHODS OF PREPARATION | EKC TECHNOLOGY, INC. | 2009-04-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110065622-A1 | NOVEL NITRILE AND AMIDOXIME COMPOUNDS AND METHODS OF PREPARATION FOR SEMICONDUCTOR PROCESSING | TNNI3K, TNK1, NIT2 | CYP2D6 3696/4885TSHR 1915/4885TPI1 1177/4885 |
| US-20090112024-A1 | STABILIZATION OF HYDROXYLAMINE CONTAINING SOLUTIONS AND METHOD FOR THEIR PREPARATION | HNMT, HMOX2, EGLN2 | CYP2D6 495/4885TSHR 1663/4885TPI1 1493/4885 |
| US-20090111965-A1 | NOVEL NITRILE AND AMIDOXIME COMPOUNDS AND METHODS OF PREPARATION | GNMT, NIT2, NNMT | CYP2D6 1003/4885TSHR 3860/4885TPI1 336/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.