Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 2/20 | 0.40 |
| ▸ | MAOB | P27338 | 2/20 | 0.40 |
| ▸ | TAAR1 | Q96RJ0 | 9/20 | 0.39 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | NOS1 | P29475 | 2/20 | 0.36 |
| ▸ | NOS2 | P35228 | 2/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | NOS3 | P29474 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.35 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.35 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.35 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.35 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.35 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.35 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.35 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10028298 | 0.90 | TAAR1 (0.55) | TAAR1CYP2D6 | |
| SCHEMBL18545334 | 0.82 | — | — | |
| Fluoride SCHEMBL27844345 | 0.80 | PNMT (0.47) | TAAR1NOS1NOS2CYP2D6NOS3 | |
| SCHEMBL187953 | 0.79 | ACHE (0.35) | — | |
| SCHEMBL8136687 | 0.73 | ALDH1A1 (0.36) | MEN1KMT2A | |
| SCHEMBL10028297 | 0.72 | CYP3A4 (0.36) | MAOAMEN1KMT2ACYP2D6 | |
| SCHEMBL21870365 | 0.72 | NR1H2 (0.42) | — | |
| SCHEMBL6332350 | 0.70 | ACHE (0.55) | TAAR1CYP2D6LMNA | |
| SCHEMBL9325469 | 0.68 | CYP3A4 (0.52) | MAOAMAOBCYP19A1MEN1KMT2A | |
| SCHEMBL1834698 | 0.68 | ALDH1A1 (0.42) | TAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7687587-B2 | Silicone composition and cured silicone resin | DOW CORNING CORPORATION (US) | 2010-03-30 | — | — | US | disclosed |
| US-20070260082-A1 | Silicone Composition and Cured Silicone Resin | DOW CORNING CORPORATION | 2007-11-08 | — | — | US | disclosed |