Sugi Predict

Sugi Predict / Compounds / SCHEMBL134474

SCHEMBL134474

SCHEMBL134474

CC(C)(C)c1cccc(I)c1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ HDAC8 Q9BY41 3/20 0.47
▸ HDAC4 P56524 1/20 0.47
▸ HDAC2 Q92769 1/20 0.47
▸ KIF11 P52732 3/20 0.45
▸ ACHE P22303 4/20 0.42
▸ RXRA P19793 1/20 0.40
▸ RXRB P28702 1/20 0.40
▸ ALDH1A1 P00352 3/20 0.39
▸ HPGD P15428 1/20 0.39
▸ ALOX15 P16050 1/20 0.39
▸ HSD17B10 Q99714 1/20 0.39
▸ TDP1 Q9NUW8 1/20 0.39
▸ NPC1 O15118 1/20 0.38
▸ PLA2G1B P04054 1/20 0.38
▸ NFKB1 P19838 1/20 0.38
▸ CASP3 P42574 1/20 0.38
▸ RAB9A P51151 1/20 0.38
▸ NFKB2 Q00653 1/20 0.38
▸ RELA Q04206 1/20 0.38
▸ SENP8 Q96LD8 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26811585 0.83 ESR1 (0.34) HDAC8HDAC4HDAC2KIF11RAB9A
SCHEMBL25975190 0.81 TAAR1 (0.37) HDAC8HDAC4HDAC2RAB9ACYP2C19
SCHEMBL16373663 0.81 TAAR1 (0.37) HDAC8HDAC4HDAC2KIF11RAB9A
SCHEMBL4124752 0.81 ESR1 (0.38) HDAC8HDAC4HDAC2ACHEALDH1A1
SCHEMBL18243516 0.81 FAAH (0.39) HDAC8HDAC4HDAC2KIF11ACHE
SCHEMBL30148546 0.81 TAS1R3 (0.37) ACHERXRAALDH1A1ESR1ESR2
SCHEMBL6899596 0.81 TAS1R3 (0.37) ACHERXRAALDH1A1ESR1ESR2
SCHEMBL129151 0.81 HDAC8 (0.56) HDAC8HDAC4HDAC2KIF11ACHE
SCHEMBL21227096 0.79 RAB9A (0.46) HDAC2ALDH1A1NPC1CASP3RAB9A
Water SCHEMBL29289408 0.78 HDAC8 (0.54) HDAC8HDAC4HDAC2KIF11ACHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 223 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111499566-A Pyridine derivative compound and preparation method thereof 南京工业大学 2020-08-07 — — CN claimed
EP-4720037-A1 CYP26B1 INHIBITOR COMPOUNDS AND METHODS OF USE THEREOF 16380026 Canada Inc. (CA) 2026-04-08 — — EP disclosed
EP-4720036-A1 CYP26B1 INHIBITOR COMPOUNDS AND METHODS OF USE THEREOF 16380026 Canada Inc. (CA) 2026-04-08 — — EP disclosed
CN-120081780-A Carbazole compound, intermediate and organic electroluminescent device 阜阳欣奕华新材料科技股份有限公司 2025-06-03 — — CN disclosed
CN-119751513-A Luminescent complex material and application thereof 深圳大学 2025-04-04 — — CN disclosed
WO-2024243692-A1 CYP26B1 INHIBITOR COMPOUNDS AND METHODS OF USE THEREOF QUEEN'S UNIVERSITY AT KINGSTON (CA) 2024-12-05 — — WO disclosed
CN-113166641-B Organic light-emitting element using polycyclic aromatic derivative compound SFC株式会社 2024-06-04 — — CN disclosed
US-20240074305-A1 TETRAHYDRONAPHTHALENE-BASED ORGANIC COMPOUND, MIXTURE, COMPOSITION, AND ORGANIC ELECTRONIC DEVICE SHENZHEN CHINA STAR OPTOELECTRONICS SEMICONDUCTOR DISPLAY TECHNOLOGY CO., LTD. (CN) 2024-02-29 — — US disclosed
US-20240074305-A1 TETRAHYDRONAPHTHALENE-BASED ORGANIC COMPOUND, MIXTURE, COMPOSITION, AND ORGANIC ELECTRONIC DEVICE SHENZHEN CHINA STAR OPTOELECTRONICS SEMICONDUCTOR DISPLAY TECHNOLOGY CO., LTD. (CN) 2024-02-29 — — US disclosed
CN-114456161-B Imidazole derivative and organic electroluminescent device thereof 长春海谱润斯科技股份有限公司 2024-01-26 — — CN disclosed
US-20040180939-A1 Acetyl 2-hydroxy-1, 3-diaminoalkanes ELAN PHARMACEUTICALS INC. 2004-09-16 — — US disclosed
WO-2004024081-A2 ACETYL 2-HYDROXY-1,3 DIAMINOALKANES ELAN PHARMACEUTICALS, INC. (US) 2004-03-25 — — WO disclosed
US-6699890-B2 N-SUBSTITUTED DIETHER ANILINE AND DIETHER DIPHENYLAMINE DERIVATIVES MEMORY PHARMACEUTICALS CORP. 2004-03-02 — — US disclosed
WO-2004009552-A1 PHOSPHODIESTERASE 4 INHIBITORS, INCLUDING N-SUBSTITUTED ANILINE AND DIPHENYLAMINE ANALOGS MEMORY PHARMACEUTICALS CORPORATION (US) 2004-01-29 — — WO disclosed
EP-1353907-A2 PHOSPHODIESTERASE 4 INHIBITORS Memory Pharmaceutical Corporation (US) 2003-10-22 — — EP disclosed
US-20030149052-A1 Phosphodiesterase 4 inhibitors MEMORY PHARMACEUTICALS CORP. 2003-08-07 — — US disclosed
US-20020151566-A1 Phosphodiesterase 4 inhibitors MEMORY PHARMACEUTICALS CORP. (US) 2002-10-17 — — US disclosed
US-6462248-B1 THROUGH CONVERSION, ISOMERIZATION AND/OR ADSORPTIVE SEPARATION OF AROMATIC COMPOUNDS TORAY INDUSTRIES, INC. (JP) 2002-10-08 — — US disclosed
WO-2002074726-A2 ANILINE DERIVATIVES USEFUL AS PHOSPHODIESTERASE 4 INHIBITORS MEMORY PHARMACEUTICALS CORPORATION (US) 2002-09-26 — — WO disclosed
EP-0985649-A2 Method for producing an aromatic compound having an alkyl group with at least three carbon atoms TORAY INDUSTRIES, INC. (JP) 2000-03-15 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030149052-A1 Phosphodiesterase 4 inhibitors PDE4A, PDE4B, PDE3A HDAC8 585/4885HDAC4 40/4885HDAC2 203/4885
US-20020151566-A1 Phosphodiesterase 4 inhibitors PDE4A, PDE4B, PDE3A HDAC8 585/4885HDAC4 40/4885HDAC2 203/4885
US-20040180939-A1 Acetyl 2-hydroxy-1, 3-diaminoalkanes BACE1, BACE2, APP HDAC8 570/4885HDAC4 416/4885HDAC2 103/4885
US-20240074305-A1 TETRAHYDRONAPHTHALENE-BASED ORGANIC COMPOUND, MIXTURE, COMPOSITION, AND ORGANIC ELECTRONIC DEVICE EXOC1, TRPA1, CYBA HDAC8 4324/4885HDAC4 4525/4885HDAC2 3053/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.