Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADH1B | P00325 | 3/20 | 0.30 |
| ▸ | ADH1C | P00326 | 3/20 | 0.30 |
| ▸ | ADH1A | P07327 | 3/20 | 0.30 |
| ▸ | ADH7 | P40394 | 3/20 | 0.30 |
| ▸ | ADH4 | P08319 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13927603 | 0.80 | — | — | |
| SCHEMBL13927602 | 0.80 | — | — | |
| SCHEMBL14074860 | 0.78 | — | — | |
| SCHEMBL1107370 | 0.78 | — | — | |
| SCHEMBL27693621 | 0.72 | ADH1B (0.38) | ADH1BADH1CADH1AADH7ADH4 | |
| SCHEMBL27429752 | 0.72 | FAP (0.34) | — | |
| SCHEMBL28623928 | 0.71 | POLB (0.32) | — | |
| SCHEMBL3344201 | 0.71 | — | — | |
| SCHEMBL14114877 | 0.71 | CARM1 (0.32) | — | |
| SCHEMBL17812990 | 0.70 | DPP4 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2340045-B1 | POLYMER CONJUGATES OF PROTEGRIN PEPTIDES | NEKTAR THERAPEUTICS (US) | 2017-04-12 | — | — | EP | disclosed |
| WO-2010033221-A1 | POLYMER CONJUGATES OF PROTEGRIN PEPTIDES | NEKTAR THERAPEUTICS (US) | 2010-03-25 | — | — | WO | disclosed |