Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.30 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15774142 | 0.78 | DPP4 (0.31) | LMNA | |
| SCHEMBL22175770 | 0.76 | ACE (0.41) | KDM4ELMNA | |
| SCHEMBL2678393 | 0.76 | ACE (0.41) | KDM4ELMNA | |
| SCHEMBL27429752 | 0.73 | FAP (0.34) | KDM4EALDH1A1 | |
| SCHEMBL14114877 | 0.71 | CARM1 (0.32) | — | |
| SCHEMBL10144562 | 0.71 | LMNA (0.34) | ALDH1A1LMNA | |
| SCHEMBL1107370 | 0.71 | — | — | |
| SCHEMBL14074860 | 0.71 | — | — | |
| SCHEMBL13448573 | 0.71 | ADH1B (0.30) | — | |
| SCHEMBL17812990 | 0.70 | DPP4 (0.32) | POLBALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112552211-B | Leonurine derivative and application thereof in preparation of medicines for preventing or treating ischemic cerebrovascular diseases | 青岛海合生物科技有限公司 | 2023-04-14 | — | — | CN | disclosed |
| CN-112552211-A | Leonurine derivative and application thereof in preparation of medicines for preventing or treating ischemic cerebrovascular diseases | 青岛海合生物科技有限公司 | 2021-03-26 | — | — | CN | disclosed |