SCHEMBL27429752

SCHEMBL27429752

CC(=O)NN1CCCC1C=O

nearest known ligand 0.34

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
FAP Q12884 3/20 0.34
DPP4 P27487 2/20 0.34
PREP P48147 2/20 0.34
NPSR1 Q6W5P4 1/20 0.31
CA1 P00915 2/20 0.31
CA2 P00918 2/20 0.31
CA12 O43570 1/20 0.31
CA9 Q16790 1/20 0.31
CHRM2 P08172 1/20 0.31
CHRM4 P08173 1/20 0.31
CHRM5 P08912 1/20 0.31
CHRM1 P11229 1/20 0.31
CHRM3 P20309 1/20 0.31
KDM4E B2RXH2 1/20 0.30
ALDH1A1 P00352 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17812990 0.82 DPP4 (0.32) DPP4ALDH1A1
SCHEMBL9128673 0.77 CA1 (0.39) CA1CA2ALDH1A1
SCHEMBL1107370 0.76
SCHEMBL13458799 0.76 L3MBTL1 (0.50) FAPDPP4PREPNPSR1ALDH1A1
SCHEMBL12409399 0.75 HDAC8 (0.43)
SCHEMBL13448573 0.72 ADH1B (0.30)
SCHEMBL14074860 0.72
SCHEMBL6355919 0.72 CA1 (0.38) FAPDPP4PREPCA1CA2
SCHEMBL1820000 0.71 CHRM2 (0.44) CHRM2CHRM4CHRM5CHRM1CHRM3
SCHEMBL4041080 0.71 CHRM2 (0.44) CHRM2CHRM4CHRM5CHRM1CHRM3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1111405-C The application of piracetam in preparation prevention and prevention intracranial hypertension medicine HE GUANGXUE (CN) 2003-06-18 CN claimed
CN-104814955-A Pharmaceutical composition for treating encephaledema SHANDONG LUOXIN PHARMACEUTICAL GROUP CO LTD 2015-08-05 CN disclosed
CN-1111405-C The application of piracetam in preparation prevention and prevention intracranial hypertension medicine HE GUANGXUE (CN) 2003-06-18 CN disclosed
CN-1250651-A Medicinal composition for preventing and curing intracranial hypertension HE GUANGXUE (CN) 2000-04-19 CN disclosed
CN-1250651-A Medicinal composition for preventing and curing intracranial hypertension HE GUANGXUE (CN) 2000-04-19 CN disclosed