Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 6/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 6/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.45 |
| ▸ | CTSD | P07339 | 1/20 | 0.45 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.43 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | HTR2B | P41595 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.41 |
| ▸ | IDO1 | P14902 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25273100 | 0.78 | TSHR (0.50) | TSHRALDH1A1TDP1HSD17B10CTSD | |
| SCHEMBL8219011 | 0.76 | TSHR (0.42) | TSHRALDH1A1TDP1HSD17B10CTSD | |
| SCHEMBL4529113 | 0.75 | ALDH1A1 (0.50) | TSHRALDH1A1TDP1HSD17B10CTSD | |
| SCHEMBL10359188 | 0.74 | TSHR (0.40) | TSHRALDH1A1TDP1HSD17B10CTSD | |
| SCHEMBL16610513 | 0.71 | TSHR (0.82) | TSHRALDH1A1TDP1HSD17B10CTSD | |
| SCHEMBL7115945 | 0.71 | ALDH1A1 (0.45) | TSHRALDH1A1TDP1HSD17B10CTSD | |
| SCHEMBL16794750 | 0.70 | TSHR (0.42) | TSHRALDH1A1TDP1HSD17B10CTSD | |
| SCHEMBL3886650 | 0.70 | TSHR (0.42) | TSHRALDH1A1TDP1HSD17B10CTSD | |
| SCHEMBL4030087 | 0.69 | NPSR1 (0.41) | TSHRALDH1A1TDP1HSD17B10CTSD | |
| SCHEMBL8214642 | 0.69 | ALDH1A1 (0.43) | TSHRALDH1A1TDP1HSD17B10CTSD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 59 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2145929-B1 | Method for manufacturing redispersible, surface-modified silicon dioxide particles | EVONIK OPERATIONS GMBH (DE) | 2020-06-24 | — | — | EP | disclosed |
| EP-2145928-B1 | Dispersion made of hydrophobic silicon dioxide particles and granulate made from same | EVONIK DEGUSSA GMBH (DE) | 2017-09-13 | — | — | EP | disclosed |
| EP-2718766-A1 | PHOTORESISTS CONTAINING POLYMER-TETHERED NANOPARTICLES | 3M Innovative Properties Company (US) | 2014-04-16 | — | — | EP | disclosed |
| EP-2670972-A2 | NOZZLE AND METHOD OF MAKING SAME | 3M Innovative Properties Company (US) | 2013-12-11 | — | — | EP | disclosed |
| CN-102099425-B | Process for preparing redispersible surface-modified silicon dioxide particles | EVONIK DEGUSSA GMBH | 2013-11-13 | — | — | CN | disclosed |
| US-8399093-B2 | Process for preparing redispersible surface-modified silicon dioxide particles | EVONIK DEGUSSA GMBH (DE) | 2013-03-19 | — | — | US | disclosed |
| WO-2012170204-A1 | PHOTORESISTS CONTAINING POLYMER-TETHERED NANOPARTICLES | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2012-12-13 | — | — | WO | disclosed |
| WO-2012106512-A2 | NOZZLE AND METHOD OF MAKING SAME | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2012-08-09 | — | — | WO | disclosed |
| EP-2480500-A1 | PROCESS FOR SURFACE MODIFICATION OF METAL OXIDE PARTICLES | Evonik Degussa GmbH (DE) | 2012-08-01 | — | — | EP | disclosed |
| US-8062820-B2 | Toner composition and method of preparing same | CABOT CORPORATION (US) | 2011-11-22 | — | — | US | disclosed |
| US-6136995-A | Process for producing aminosilane compounds | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2000-10-24 | — | — | US | disclosed |
| EP-0112434-B1 | HYDROGEN BEARING SILYL CARBAMATES | UNION CARBIDE CORPORATION (US) | 1988-08-17 | — | — | EP | disclosed |
| EP-0273456-A2 | Vapor phase alcoholysis of aminosilanes and carbamatosilanes | UNION CARBIDE CORPORATION (US) | 1988-07-06 | — | — | EP | disclosed |
| US-4730074-A | Vapor phase alcoholysis of aminosilanes and carbamatosilanes | UNION CARBIDE CORPORATION (US) | 1988-03-08 | — | — | US | disclosed |
| EP-0098912-B1 | PROCESS FOR THE PREPARATION OF ALKOXYHYDRIDOSILANES | UNION CARBIDE CORPORATION (US) | 1986-04-23 | — | — | EP | disclosed |
| EP-0098911-B1 | IMPROVED PROCESS FOR THE PREPARATION OF OXIMATOHYDRIDOSILANES AND AMINOXYHYDRIDOSILANES | UNION CARBIDE CORPORATION (US) | 1986-04-16 | — | — | EP | disclosed |
| EP-0098911-A1 | Improved process for the preparation of oximatohydridosilanes and aminoxyhydridosilanes | UNION CARBIDE CORPORATION (US) | 1984-01-25 | — | — | EP | disclosed |
| EP-0098912-A1 | Process for the preparation of alkoxyhydridosilanes | UNION CARBIDE CORPORATION (US) | 1984-01-25 | — | — | EP | disclosed |
| US-4395564-A | REACTING AN ALCOHOL WITH SILYL-AMINE | UNION CARBIDE CORPORATION (US) | 1983-07-26 | — | — | US | disclosed |
| US-4384131-A | Process for the preparation of oximatohydridosilanes and aminoxyhydridosilanes | UNION CARBIDE CORPORATION (US) | 1983-05-17 | — | — | US | disclosed |