SCHEMBL4529113

SCHEMBL4529113

c1ccc(N[SiH](Nc2ccccc2)Nc2ccccc2)cc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 9/20 0.50
HSD17B10 Q99714 5/20 0.50
TDP1 Q9NUW8 4/20 0.50
CTSD P07339 1/20 0.50
TSHR P16473 4/20 0.47
PTGS2 P35354 2/20 0.47
ALOX12 P18054 2/20 0.47
L3MBTL1 Q9Y468 2/20 0.47
ALOX15 P16050 2/20 0.47
PTGS1 P23219 1/20 0.47
SLC6A2 P23975 1/20 0.47
MAPK1 P28482 1/20 0.47
HTR2B P41595 1/20 0.47
CYP3A4 P08684 5/20 0.45
IDO1 P14902 3/20 0.45
CYP1A2 P05177 2/20 0.45
CYP2C9 P11712 2/20 0.45
CYP2C19 P33261 2/20 0.45
LMNA P02545 1/20 0.45
CYP2D6 P10635 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1345309 0.75 TSHR (0.48) ALDH1A1HSD17B10TDP1CTSDTSHR
SCHEMBL7115945 0.75 ALDH1A1 (0.45) ALDH1A1HSD17B10TDP1CTSDTSHR
SCHEMBL8214642 0.73 ALDH1A1 (0.43) ALDH1A1HSD17B10TDP1CTSDTSHR
SCHEMBL25273100 0.71 TSHR (0.50) ALDH1A1HSD17B10TDP1CTSDTSHR
SCHEMBL196159 0.69
Diphenylamine SCHEMBL29116726 0.69 HSD17B10 (0.86) ALDH1A1HSD17B10TDP1CTSDTSHR
Diphenylamine SCHEMBL229 0.67 HSD17B10 (1.00) ALDH1A1HSD17B10TDP1CTSDTSHR
SCHEMBL19737269 0.67 ALDH1A1 (1.00) ALDH1A1HSD17B10TDP1CTSDTSHR
Diphenylamine SCHEMBL3003404 0.67 HSD17B10 (1.00) ALDH1A1HSD17B10TDP1CTSDTSHR
Diphenylamine SCHEMBL301493 0.67 HSD17B10 (1.00) ALDH1A1HSD17B10TDP1CTSDTSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 38 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116253580-A Siliceous decorative concrete protective agent 德清扬泰建筑材料有限公司 2023-06-13 CN claimed
CN-112047745-A Composite refractory fiber and preparation method thereof 山东金三河新材料科技有限公司 2020-12-08 CN claimed
CN-109455241-B Transposition pole climbing mechanism 国家电网公司 2020-09-29 CN claimed
EP-2111483-B1 CORROSION INHIBITOR ASCOTEC (FR) 2020-04-29 EP claimed
US-20240213017-A1 METHOD OF MANUFACTURING INTEGRATED CIRCUIT DEVICE SAMSUNG ELECTRONICS CO., LTD. (KR) 2024-06-27 US disclosed
CN-117229745-A Double-component sealing water-blocking adhesive and preparation method and application thereof 苏州赛伍应用技术股份有限公司 2023-12-15 CN disclosed
CN-116253580-A Siliceous decorative concrete protective agent 德清扬泰建筑材料有限公司 2023-06-13 CN disclosed
CN-112047745-A Composite refractory fiber and preparation method thereof 山东金三河新材料科技有限公司 2020-12-08 CN disclosed
CN-109455241-B Transposition pole climbing mechanism 国家电网公司 2020-09-29 CN disclosed
EP-2111483-B1 CORROSION INHIBITOR ASCOTEC (FR) 2020-04-29 EP disclosed
EP-1624851-B1 HAIR CARE APPLICATIONS OF EMULSIONS CONTAINING ELASTOMERIC SILANES AND SILOXANES WITH NITROGEN ATOMS DOW CORNING (US) 2014-05-28 EP disclosed
US-7902293-B2 Method of preparing emulsions containing elastomeric silanes and siloxanes having quaternary ammonium groups DOW CORNING CORPORATION (US) 2011-03-08 US disclosed
EP-0273456-A2 Vapor phase alcoholysis of aminosilanes and carbamatosilanes UNION CARBIDE CORPORATION (US) 1988-07-06 EP disclosed
US-4730074-A Vapor phase alcoholysis of aminosilanes and carbamatosilanes UNION CARBIDE CORPORATION (US) 1988-03-08 US disclosed
EP-0098912-B1 PROCESS FOR THE PREPARATION OF ALKOXYHYDRIDOSILANES UNION CARBIDE CORPORATION (US) 1986-04-23 EP disclosed
EP-0098911-B1 IMPROVED PROCESS FOR THE PREPARATION OF OXIMATOHYDRIDOSILANES AND AMINOXYHYDRIDOSILANES UNION CARBIDE CORPORATION (US) 1986-04-16 EP disclosed
EP-0098911-A1 Improved process for the preparation of oximatohydridosilanes and aminoxyhydridosilanes UNION CARBIDE CORPORATION (US) 1984-01-25 EP disclosed
EP-0098912-A1 Process for the preparation of alkoxyhydridosilanes UNION CARBIDE CORPORATION (US) 1984-01-25 EP disclosed
US-4395564-A REACTING AN ALCOHOL WITH SILYL-AMINE UNION CARBIDE CORPORATION (US) 1983-07-26 US disclosed
US-4384131-A Process for the preparation of oximatohydridosilanes and aminoxyhydridosilanes UNION CARBIDE CORPORATION (US) 1983-05-17 US disclosed