SCHEMBL3886650

SCHEMBL3886650

CO[SiH](Nc1ccccc1)OC

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.42
TDP1 Q9NUW8 4/20 0.39
HSD17B10 Q99714 3/20 0.39
ALDH1A1 P00352 3/20 0.39
CTSD P07339 1/20 0.39
MAPT P10636 3/20 0.38
ALOX15 P16050 2/20 0.38
PTGS2 P35354 2/20 0.38
MAPK1 P28482 2/20 0.38
L3MBTL1 Q9Y468 2/20 0.38
ALOX12 P18054 1/20 0.38
PTGS1 P23219 1/20 0.38
SLC6A2 P23975 1/20 0.38
HTR2B P41595 1/20 0.38
IDO1 P14902 3/20 0.36
CYP1A2 P05177 2/20 0.36
CYP2C19 P33261 2/20 0.36
LMNA P02545 2/20 0.36
CYP3A4 P08684 1/20 0.36
CYP2D6 P10635 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3891707 0.75 NPSR1 (0.42) TSHRTDP1HSD17B10ALDH1A1CTSD
SCHEMBL1345309 0.70 TSHR (0.48) TSHRTDP1HSD17B10ALDH1A1CTSD
SCHEMBL1185274 0.70 GAA (0.36) TSHRTDP1HSD17B10ALDH1A1CTSD
SCHEMBL4529113 0.69 ALDH1A1 (0.50) TSHRTDP1HSD17B10ALDH1A1CTSD
SCHEMBL1172401 0.69 HPGD (0.45) TSHRTDP1ALDH1A1MAPTMAPK1
SCHEMBL1255978 0.69 TDP1 (0.37) TSHRTDP1HSD17B10ALDH1A1CTSD
SCHEMBL142327 0.68 TSHR (0.67) TSHRTDP1HSD17B10ALDH1A1CTSD
Diphenylamine SCHEMBL3979440 0.67 HSD17B10 (0.75) TSHRTDP1HSD17B10ALDH1A1MAPT
SCHEMBL4441968 0.67 TSHR (0.64) TSHRTDP1HSD17B10ALDH1A1CTSD
SCHEMBL25273100 0.67 TSHR (0.50) TSHRTDP1HSD17B10ALDH1A1CTSD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7572303-B2 A symmetrical dialkyl carbonate, a metal, borong, silicon, or group 7 compound, a hydrogen or hydrocarbon-based fuel, an oxidizer, and a metallic cocatalyst; minimized hydrolysis; improved combustion and storage stability OCTANE INTERNATIONAL, LTD. (US) 2009-08-11 US disclosed
EP-0954558-B1 FUEL COMPOSITIONS EXHIBITING IMPROVED FUEL STABILITY ORR WILLIAM C (US) 2006-06-14 EP disclosed
US-20050044778-A1 Fuel compositions employing catalyst combustion structure OCTANE INTERNATIONAL, LTD. 2005-03-03 US disclosed
US-20040237384-A1 Fuel compositions exhibiting improved fuel stability OCTANE INTERNATIONAL, LTD. 2004-12-02 US disclosed
EP-0954558-A1 FUEL COMPOSITIONS EXHIBITING IMPROVED FUEL STABILITY ORR, William C. (US) 1999-11-10 EP disclosed
WO-1998026028-A1 FUEL COMPOSITIONS EXHIBITING IMPROVED FUEL STABILITY ORR WILLIAM C (US) 1998-06-18 WO disclosed