Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACLY | P53396 | 2/20 | 0.63 |
| ▸ | ACACA | Q13085 | 2/20 | 0.63 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.60 |
| ▸ | HSD11B1 | P28845 | 6/20 | 0.55 |
| ▸ | HSD11B2 | P80365 | 1/20 | 0.53 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1878720 | 1.00 | ACLY (0.63) | ACLYACACAPTPN11HSD11B1HSD11B2 | |
| SCHEMBL982765 | 1.00 | ACLY (0.63) | ACLYACACAPTPN11HSD11B1HSD11B2 | |
| SCHEMBL1653320 | 1.00 | ACLY (0.63) | ACLYACACAPTPN11HSD11B1HSD11B2 | |
| SCHEMBL1878721 | 1.00 | ACLY (0.63) | ACLYACACAPTPN11HSD11B1HSD11B2 | |
| SCHEMBL14047057 | 1.00 | ACLY (0.63) | ACLYACACAPTPN11HSD11B1HSD11B2 | |
| SCHEMBL14520017 | 1.00 | ACLY (0.63) | ACLYACACAPTPN11HSD11B1HSD11B2 | |
| SCHEMBL12152345 | 1.00 | ACLY (0.63) | ACLYACACAPTPN11HSD11B1HSD11B2 | |
| SCHEMBL13420256 | 1.00 | ACLY (0.63) | ACLYACACAPTPN11HSD11B1HSD11B2 | |
| SCHEMBL13801861 | 1.00 | ACLY (0.63) | ACLYACACAPTPN11HSD11B1HSD11B2 | |
| SCHEMBL11408854 | 1.00 | ACLY (0.63) | ACLYACACAPTPN11HSD11B1HSD11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100056487-A1 | MODULATORS OF AMYLOID-BETA PRODUCTION | SATORI PHARMACEUTICALS, INC. (US) | 2010-03-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100056487-A1 | MODULATORS OF AMYLOID-BETA PRODUCTION | APP, BACE1, BACE2 | ACLY 668/4885ACACA 195/4885PTPN11 4386/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.