SCHEMBL982765

SCHEMBL982765

C=C(CC[C@@H](C)[C@H]1CC[C@@]2(C)C3CC[C@H]4C(C)(C)[C@@H](O)CC[C@@]45C[C@@]35CC[C@]12C)C(C)C

nearest known ligand 0.63

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ACLY P53396 2/20 0.63
▸ ACACA Q13085 2/20 0.63
▸ PTPN11 Q06124 1/20 0.60
▸ HSD11B1 P28845 6/20 0.55
▸ HSD11B2 P80365 1/20 0.53
▸ ESR2 Q92731 1/20 0.40
▸ PTGS1 P23219 1/20 0.40
▸ PTGS2 P35354 1/20 0.40
▸ CYP2C19 P33261 1/20 0.39
▸ HIF1A Q16665 1/20 0.39
▸ NR1H3 Q13133 1/20 0.38
▸ MEN1 O00255 1/20 0.37
▸ KMT2A Q03164 1/20 0.37
▸ PTPN1 P18031 1/20 0.37
▸ USP2 O75604 1/20 0.37
▸ ALDH1A1 P00352 1/20 0.37
▸ LMNA P02545 1/20 0.37
▸ CYP3A4 P08684 1/20 0.37
▸ MAPT P10636 1/20 0.37
▸ ALOX15 P16050 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13455191 1.00 ACLY (0.63) ACLYACACAPTPN11HSD11B1HSD11B2
SCHEMBL1878720 1.00 ACLY (0.63) ACLYACACAPTPN11HSD11B1HSD11B2
SCHEMBL1653320 1.00 ACLY (0.63) ACLYACACAPTPN11HSD11B1HSD11B2
SCHEMBL1878721 1.00 ACLY (0.63) ACLYACACAPTPN11HSD11B1HSD11B2
SCHEMBL14047057 1.00 ACLY (0.63) ACLYACACAPTPN11HSD11B1HSD11B2
SCHEMBL14520017 1.00 ACLY (0.63) ACLYACACAPTPN11HSD11B1HSD11B2
SCHEMBL12152345 1.00 ACLY (0.63) ACLYACACAPTPN11HSD11B1HSD11B2
SCHEMBL13420256 1.00 ACLY (0.63) ACLYACACAPTPN11HSD11B1HSD11B2
SCHEMBL13801861 1.00 ACLY (0.63) ACLYACACAPTPN11HSD11B1HSD11B2
SCHEMBL11408854 1.00 ACLY (0.63) ACLYACACAPTPN11HSD11B1HSD11B2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1301460-B9 METHOD FOR PREPARING A FATTY SUBSTANCE ESTER AND USE THEREOF IN PHARMACEUTICS, COSMETICS OR FOOD INDUSTRY EXPANSCIENCE LAB (FR) 2009-03-11 — — EP claimed
EP-1301460-B1 METHOD FOR PREPARING A FATTY SUBSTANCE ESTER AND USE THEREOF IN PHARMACEUTICS, COSMETICS OR FOOD INDUSTRY EXPANSCIENCE LAB (FR) 2008-08-06 — — EP claimed
EP-0166542-A2 Triterpenyl esters of organic acids, process for their production, and hypolipidemic agents composed of them AMANO PHARMACEUTICAL CO., LTD. (JP) 1986-01-02 — — EP claimed
CN-107582899-B Mongolian medicine for clearing heat and stopping bleeding and its preparing process 内蒙古民族大学附属医院 2021-01-15 — — CN disclosed
CN-109731026-A A kind of externally used Mongolian medicine of set a broken bone and preparation method thereof 内蒙古民族大学附属医院 2019-05-10 — — CN disclosed
CN-109394824-A A kind of anaesthetic of bone-setting pain stopping and preparation method thereof 内蒙古民族大学附属医院 2019-03-01 — — CN disclosed
EP-3120854-A1 CYCLOARTENOL-CONTAINING COMPOSITION Kao Corporation (JP) 2017-01-25 — — EP disclosed
US-20170014430-A1 Cycloartenol-Containing Composition KAO CORPORATION (JP) 2017-01-19 — — US disclosed
CN-106261429-A A kind of clear and rich beverage composition and preparation method thereof 陈桂玲 2017-01-04 — — CN disclosed
US-9200029-B2 Process for production of triterpene alcohol KAO CORPORATION (JP) 2015-12-01 — — US disclosed
EP-2607372-B1 PROCESS FOR PRODUCTION OF TRITERPENE ALCOHOL KAO CORP (JP) 2015-10-28 — — EP disclosed
EP-2262516-A2 COMPOSITION CONTAINING CAPSICUM FOR TREATING A SKIN DISORDER Rezai-Fard, Ali (GB) 2010-12-22 — — EP disclosed
WO-2010082689-A2 GIP-INCREASE INHIBITOR KAO CORPORATION (JP) 2010-07-22 — — WO disclosed
WO-2009090394-A2 COMPOSITION FOR TREATING A SKIN DISORDER REZAI-FARD ALI (GB) 2009-07-23 — — WO disclosed
US-7511010-B2 Pharmaceutical or cosmetic composition and use of a PKC inhibitor with an MMP inhibitor for inhibiting Langerhans' cell migration LABORATOIRES EXPANSCIENCE (FR) 2009-03-31 — — US disclosed
US-20080221017-A1 Pharmaceutical or cosmetic composition and use of a PKC inhibitor with an MMP inhibitor for inhibiting langerhans cell migration LABORATOIRES EXPANSCIENCE 2008-09-11 — — US disclosed
US-6828451-B2 Fatty substance is esterified with alcohol selected from sterols, stanols, 4-methylsterols and their hydrogenated homologs, triterpene alcohols, and mixtures, in presence of solid lanthanide metal oxide catalyst LABORATOIRES EXPANSCIENCE (FR) 2004-12-07 — — US disclosed
US-20040067910-A1 Pharmaceutical or cosmetic composition and use of a pkc inhibitor with an mmp inhibitor for inhibiting langerhans' cell migration LABORATOIRES EXPANSCIENCE (FR) 2004-04-08 — — US disclosed
US-5869708-A Process for the isolation of oryzanols from crude dark acid oil (rice bran) COUNCIL FOR SCIENTIFIC & INDUSTRIAL RESEARCH (IN) 1999-02-09 — — US disclosed
EP-0166542-A2 Triterpenyl esters of organic acids, process for their production, and hypolipidemic agents composed of them AMANO PHARMACEUTICAL CO., LTD. (JP) 1986-01-02 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040067910-A1 Pharmaceutical or cosmetic composition and use of a pkc inhibitor with an mmp inhibitor for inhibiting langerhans' cell migration MMP1, MMP2, MMP13 ACLY 3600/4885ACACA 964/4885PTPN11 1380/4885
US-20080221017-A1 Pharmaceutical or cosmetic composition and use of a PKC inhibitor with an MMP inhibitor for inhibiting langerhans cell migration MMP1, MMP13, MMP2 ACLY 3624/4885ACACA 865/4885PTPN11 1494/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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