Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACLY | P53396 | 2/20 | 0.63 |
| ▸ | ACACA | Q13085 | 2/20 | 0.63 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.60 |
| ▸ | HSD11B1 | P28845 | 6/20 | 0.55 |
| ▸ | HSD11B2 | P80365 | 1/20 | 0.53 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13455191 | 1.00 | ACLY (0.63) | ACLYACACAPTPN11HSD11B1HSD11B2 | |
| SCHEMBL1878720 | 1.00 | ACLY (0.63) | ACLYACACAPTPN11HSD11B1HSD11B2 | |
| SCHEMBL982765 | 1.00 | ACLY (0.63) | ACLYACACAPTPN11HSD11B1HSD11B2 | |
| SCHEMBL1653320 | 1.00 | ACLY (0.63) | ACLYACACAPTPN11HSD11B1HSD11B2 | |
| SCHEMBL14047057 | 1.00 | ACLY (0.63) | ACLYACACAPTPN11HSD11B1HSD11B2 | |
| SCHEMBL14520017 | 1.00 | ACLY (0.63) | ACLYACACAPTPN11HSD11B1HSD11B2 | |
| SCHEMBL12152345 | 1.00 | ACLY (0.63) | ACLYACACAPTPN11HSD11B1HSD11B2 | |
| SCHEMBL13420256 | 1.00 | ACLY (0.63) | ACLYACACAPTPN11HSD11B1HSD11B2 | |
| SCHEMBL13801861 | 1.00 | ACLY (0.63) | ACLYACACAPTPN11HSD11B1HSD11B2 | |
| SCHEMBL11408854 | 1.00 | ACLY (0.63) | ACLYACACAPTPN11HSD11B1HSD11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 82 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210121383-A1 | COMPOSITION FOR ANTI-AGING | MORINAGA MILK INDUSTRY CO., LTD. (JP) | 2021-04-29 | — | — | US | claimed |
| EP-3777865-A1 | ANTI-AGING COMPOSITION | Morinaga Milk Industry Co., Ltd. (JP) | 2021-02-17 | — | — | EP | claimed |
| WO-2019188491-A1 | ANTI-AGING COMPOSITION | 森永乳業株式会社 | 2019-10-03 | — | — | WO | claimed |
| WO-2019188490-A1 | COMPOSITION FOR IMPROVING ULTRAVIOLET RAY RESISTANCE | 森永乳業株式会社 | 2019-10-03 | — | — | WO | claimed |
| EP-2377874-B1 | Compositions comprising a lophenol | MORINAGA MILK INDUSTRY CO LTD (JP) | 2019-01-23 | — | — | EP | claimed |
| EP-1882472-B1 | DRUGS, FOOD OR DRINK FOR IMPROVING PANCREATIC FUNCTIONS | MORINAGA MILK INDUSTRY CO LTD (JP) | 2018-08-22 | — | — | EP | claimed |
| EP-1930014-B1 | AGENT FOR AMELIORATION OF INSULIN RESISTANCE | MORINAGA MILK INDUSTRY CO LTD (JP) | 2017-03-01 | — | — | EP | claimed |
| US-8877265-B2 | Method of producing aloe vera extract | MORINAGA MILK INDUSTRY CO., LTD. (JP) | 2014-11-04 | — | — | US | claimed |
| US-8709512-B2 | Method for treating hyperglycemia | MORINAGA MILK INDUSTRY CO., LTD. (JP) | 2014-04-29 | — | — | US | claimed |
| EP-1795200-B1 | MEDICINE AND FOOD/BEVERAGE FOR AMELIORATING HYPERGLYCEMIA | MORINAGA MILK INDUSTRY CO LTD (JP) | 2014-04-23 | — | — | EP | claimed |
| US-20110104314-A1 | ALOE VERA EXTRACT, METHOD OF PRODUCING ALOE VERA EXTRACT, AND HYPERGLYCEMIA IMPROVING AGENT | MORINAGA MILK INDUSTRY CO., LTD. (JP) | 2011-05-05 | — | — | US | claimed |
| EP-2206509-A1 | Aloe vera extract, method of producing aloe vera extract, and hyperglycemia improving agent | Morinaga Milk Industry Co., Ltd. (JP) | 2010-07-14 | — | — | EP | claimed |
| US-20100035851-A1 | AGENT FOR IMPROVING INSULIN RESISTANCE | MORINAGA MILK INDUSTRY CO., LTD (JP) | 2010-02-11 | — | — | US | claimed |
| US-20090054354-A1 | DRUG AND FOOD OR DRINK FOR IMPROVING PANCREATIC FUNCTIONS | MORINAGA MILK INDUSTRY CO., LTD. (JP) | 2009-02-26 | — | — | US | claimed |
| US-20090004307-A1 | Aloe Vera Extract, Method of Producing Aloe Vera Extract, and Hyperglycemia Improving Agent | MORINAGA MILK INDUSTRY CO., LTD. (JP) | 2009-01-01 | — | — | US | claimed |
| EP-1952817-A1 | ALOE VERA EXTRACT, PROCESS FOR PRODUCTION OF ALOE VERA EXTRACT, AND AMELIORATING AGENT FOR HYPERGLYCEMIA | Morinaga Milk Industry Co., Ltd. (JP) | 2008-08-06 | — | — | EP | claimed |
| EP-1930014-A1 | AGENT FOR AMELIORATION OF INSULIN RESISTANCE | Morinaga Milk Industry Co., Ltd. (JP) | 2008-06-11 | — | — | EP | claimed |
| EP-1882472-A1 | DRUGS, FOOD OR DRINK FOR IMPROVING PANCREATIC FUNCTIONS | Morinaga Milk Industry Co., Ltd. (JP) | 2008-01-30 | — | — | EP | claimed |
| US-20070196435-A1 | Drug and food or drink for improving hyperglycemia | MORINAGA MILK INDUSTRY CO., LTD. (JP) | 2007-08-23 | — | — | US | claimed |
| EP-1795200-A1 | MEDICINE AND FOOD/BEVERAGE FOR AMELIORATING HYPERGLYCEMIA | MORINAGA MILK INDUSTRY CO., LTD. (JP) | 2007-06-13 | — | — | EP | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100035851-A1 | AGENT FOR IMPROVING INSULIN RESISTANCE | GPR119, IRS1, LIPE | ACLY 159/4885ACACA 290/4885PTPN11 1140/4885 |
| US-20090054354-A1 | DRUG AND FOOD OR DRINK FOR IMPROVING PANCREATIC FUNCTIONS | GPR119, PNLIP, AMY2A | ACLY 1113/4885ACACA 449/4885PTPN11 3615/4885 |
| US-20070196435-A1 | Drug and food or drink for improving hyperglycemia | GPR119, SLC2A9, GCKR | ACLY 565/4885ACACA 305/4885PTPN11 3489/4885 |
| US-20090004307-A1 | Aloe Vera Extract, Method of Producing Aloe Vera Extract, and Hyperglycemia Improving Agent | ALOX12, ALOX15, ALOX15B | ACLY 620/4885ACACA 95/4885PTPN11 1944/4885 |
| US-20210121383-A1 | COMPOSITION FOR ANTI-AGING | GLA, GLB1, LIMS1 | ACLY 1282/4885ACACA 119/4885PTPN11 2857/4885 |
| US-20110104314-A1 | ALOE VERA EXTRACT, METHOD OF PRODUCING ALOE VERA EXTRACT, AND HYPERGLYCEMIA IMPROVING AGENT | ALOX12, ALOX15, ALOX15B | ACLY 620/4885ACACA 95/4885PTPN11 1944/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.