SCHEMBL1878720

SCHEMBL1878720

C=C(CC[C@@H](C)[C@H]1CC[C@@]2(C)[C@@H]3CC[C@H]4C(C)(C)C(O)CC[C@@]45C[C@]35CC[C@]12C)C(C)C

nearest known ligand 0.63

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ACLY P53396 2/20 0.63
▸ ACACA Q13085 2/20 0.63
▸ PTPN11 Q06124 1/20 0.60
▸ HSD11B1 P28845 6/20 0.55
▸ HSD11B2 P80365 1/20 0.53
▸ ESR2 Q92731 1/20 0.40
▸ PTGS1 P23219 1/20 0.40
▸ PTGS2 P35354 1/20 0.40
▸ CYP2C19 P33261 1/20 0.39
▸ HIF1A Q16665 1/20 0.39
▸ NR1H3 Q13133 1/20 0.38
▸ MEN1 O00255 1/20 0.37
▸ KMT2A Q03164 1/20 0.37
▸ PTPN1 P18031 1/20 0.37
▸ USP2 O75604 1/20 0.37
▸ ALDH1A1 P00352 1/20 0.37
▸ LMNA P02545 1/20 0.37
▸ CYP3A4 P08684 1/20 0.37
▸ MAPT P10636 1/20 0.37
▸ ALOX15 P16050 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13455191 1.00 ACLY (0.63) ACLYACACAPTPN11HSD11B1HSD11B2
SCHEMBL982765 1.00 ACLY (0.63) ACLYACACAPTPN11HSD11B1HSD11B2
SCHEMBL1653320 1.00 ACLY (0.63) ACLYACACAPTPN11HSD11B1HSD11B2
SCHEMBL1878721 1.00 ACLY (0.63) ACLYACACAPTPN11HSD11B1HSD11B2
SCHEMBL14047057 1.00 ACLY (0.63) ACLYACACAPTPN11HSD11B1HSD11B2
SCHEMBL14520017 1.00 ACLY (0.63) ACLYACACAPTPN11HSD11B1HSD11B2
SCHEMBL12152345 1.00 ACLY (0.63) ACLYACACAPTPN11HSD11B1HSD11B2
SCHEMBL13420256 1.00 ACLY (0.63) ACLYACACAPTPN11HSD11B1HSD11B2
SCHEMBL13801861 1.00 ACLY (0.63) ACLYACACAPTPN11HSD11B1HSD11B2
SCHEMBL11408854 1.00 ACLY (0.63) ACLYACACAPTPN11HSD11B1HSD11B2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 82 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210121383-A1 COMPOSITION FOR ANTI-AGING MORINAGA MILK INDUSTRY CO., LTD. (JP) 2021-04-29 — — US claimed
EP-3777865-A1 ANTI-AGING COMPOSITION Morinaga Milk Industry Co., Ltd. (JP) 2021-02-17 — — EP claimed
WO-2019188490-A1 COMPOSITION FOR IMPROVING ULTRAVIOLET RAY RESISTANCE 森永乳業株式会社 2019-10-03 — — WO claimed
WO-2019188491-A1 ANTI-AGING COMPOSITION 森永乳業株式会社 2019-10-03 — — WO claimed
EP-2377874-B1 Compositions comprising a lophenol MORINAGA MILK INDUSTRY CO LTD (JP) 2019-01-23 — — EP claimed
EP-1882472-B1 DRUGS, FOOD OR DRINK FOR IMPROVING PANCREATIC FUNCTIONS MORINAGA MILK INDUSTRY CO LTD (JP) 2018-08-22 — — EP claimed
EP-1930014-B1 AGENT FOR AMELIORATION OF INSULIN RESISTANCE MORINAGA MILK INDUSTRY CO LTD (JP) 2017-03-01 — — EP claimed
US-8877265-B2 Method of producing aloe vera extract MORINAGA MILK INDUSTRY CO., LTD. (JP) 2014-11-04 — — US claimed
US-8709512-B2 Method for treating hyperglycemia MORINAGA MILK INDUSTRY CO., LTD. (JP) 2014-04-29 — — US claimed
EP-1795200-B1 MEDICINE AND FOOD/BEVERAGE FOR AMELIORATING HYPERGLYCEMIA MORINAGA MILK INDUSTRY CO LTD (JP) 2014-04-23 — — EP claimed
US-20110104314-A1 ALOE VERA EXTRACT, METHOD OF PRODUCING ALOE VERA EXTRACT, AND HYPERGLYCEMIA IMPROVING AGENT MORINAGA MILK INDUSTRY CO., LTD. (JP) 2011-05-05 — — US claimed
EP-2206509-A1 Aloe vera extract, method of producing aloe vera extract, and hyperglycemia improving agent Morinaga Milk Industry Co., Ltd. (JP) 2010-07-14 — — EP claimed
US-20100035851-A1 AGENT FOR IMPROVING INSULIN RESISTANCE MORINAGA MILK INDUSTRY CO., LTD (JP) 2010-02-11 — — US claimed
US-20090054354-A1 DRUG AND FOOD OR DRINK FOR IMPROVING PANCREATIC FUNCTIONS MORINAGA MILK INDUSTRY CO., LTD. (JP) 2009-02-26 — — US claimed
US-20090004307-A1 Aloe Vera Extract, Method of Producing Aloe Vera Extract, and Hyperglycemia Improving Agent MORINAGA MILK INDUSTRY CO., LTD. (JP) 2009-01-01 — — US claimed
EP-1952817-A1 ALOE VERA EXTRACT, PROCESS FOR PRODUCTION OF ALOE VERA EXTRACT, AND AMELIORATING AGENT FOR HYPERGLYCEMIA Morinaga Milk Industry Co., Ltd. (JP) 2008-08-06 — — EP claimed
EP-1930014-A1 AGENT FOR AMELIORATION OF INSULIN RESISTANCE Morinaga Milk Industry Co., Ltd. (JP) 2008-06-11 — — EP claimed
EP-1882472-A1 DRUGS, FOOD OR DRINK FOR IMPROVING PANCREATIC FUNCTIONS Morinaga Milk Industry Co., Ltd. (JP) 2008-01-30 — — EP claimed
US-20070196435-A1 Drug and food or drink for improving hyperglycemia MORINAGA MILK INDUSTRY CO., LTD. (JP) 2007-08-23 — — US claimed
EP-1795200-A1 MEDICINE AND FOOD/BEVERAGE FOR AMELIORATING HYPERGLYCEMIA MORINAGA MILK INDUSTRY CO., LTD. (JP) 2007-06-13 — — EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100035851-A1 AGENT FOR IMPROVING INSULIN RESISTANCE GPR119, IRS1, LIPE ACLY 159/4885ACACA 290/4885PTPN11 1140/4885
US-20090054354-A1 DRUG AND FOOD OR DRINK FOR IMPROVING PANCREATIC FUNCTIONS GPR119, PNLIP, AMY2A ACLY 1113/4885ACACA 449/4885PTPN11 3615/4885
US-20070196435-A1 Drug and food or drink for improving hyperglycemia GPR119, SLC2A9, GCKR ACLY 565/4885ACACA 305/4885PTPN11 3489/4885
US-20090004307-A1 Aloe Vera Extract, Method of Producing Aloe Vera Extract, and Hyperglycemia Improving Agent ALOX12, ALOX15, ALOX15B ACLY 620/4885ACACA 95/4885PTPN11 1944/4885
US-20210121383-A1 COMPOSITION FOR ANTI-AGING GLA, GLB1, LIMS1 ACLY 1282/4885ACACA 119/4885PTPN11 2857/4885
US-20110104314-A1 ALOE VERA EXTRACT, METHOD OF PRODUCING ALOE VERA EXTRACT, AND HYPERGLYCEMIA IMPROVING AGENT ALOX12, ALOX15, ALOX15B ACLY 620/4885ACACA 95/4885PTPN11 1944/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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