Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 8/20 | 0.56 |
| ▸ | MAPT | P10636 | 6/20 | 0.56 |
| ▸ | NPC1 | O15118 | 8/20 | 0.47 |
| ▸ | APP | P05067 | 5/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.46 |
| ▸ | SNCA | P37840 | 1/20 | 0.45 |
| ▸ | INSR | P06213 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | ACP1 | P24666 | 1/20 | 0.40 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.40 |
| ▸ | CDK2 | P24941 | 1/20 | 0.40 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.40 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12566874 | 0.86 | MAPT (0.47) | RAB9AMAPTNPC1KDM4EGLA | |
| SCHEMBL11173803 | 0.82 | MAPT (0.56) | RAB9AMAPTNPC1APPKDM4E | |
| SCHEMBL22694934 | 0.81 | RAB9A (0.54) | RAB9AMAPTNPC1APPKDM4E | |
| SCHEMBL17038163 | 0.79 | RAB9A (0.53) | RAB9AMAPTNPC1APPKDM4E | |
| SCHEMBL13458053 | 0.79 | HTT (0.56) | MAPTAPPGAADYRK1ASNCA | |
| SCHEMBL12545463 | 0.78 | CYP1A2 (0.59) | RAB9AMAPTNPC1APPDYRK1A | |
| Cyanide SCHEMBL22130066 | 0.78 | RAB9A (0.51) | RAB9AMAPTNPC1APPKDM4E | |
| SCHEMBL12566875 | 0.76 | INSR (0.42) | RAB9AMAPTNPC1APPKDM4E | |
| SCHEMBL27365085 | 0.76 | RAB9A (0.61) | RAB9AMAPTNPC1APPKDM4E | |
| SCHEMBL13444809 | 0.75 | MAPT (0.69) | RAB9AMAPTNPC1APPKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010024463-A1 | THERMOPLASTIC RESIN, ORGANIC-INORGANIC HYBRID COMPOSITION AND OPTICAL PARTS | FUJIFILM CORPORATION (JP) | 2010-03-04 | — | — | WO | disclosed |