Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | APP | P05067 | 8/20 | 0.50 |
| ▸ | SNCA | P37840 | 2/20 | 0.50 |
| ▸ | CA12 | O43570 | 1/20 | 0.49 |
| ▸ | CA1 | P00915 | 1/20 | 0.49 |
| ▸ | CA2 | P00918 | 1/20 | 0.49 |
| ▸ | CA4 | P22748 | 1/20 | 0.49 |
| ▸ | CA6 | P23280 | 1/20 | 0.49 |
| ▸ | CA5A | P35218 | 1/20 | 0.49 |
| ▸ | CA9 | Q16790 | 1/20 | 0.49 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.49 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.49 |
| ▸ | SULT1A1 | P50225 | 3/20 | 0.47 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.46 |
| ▸ | HSD17B1 | P14061 | 4/20 | 0.45 |
| ▸ | HSD17B2 | P37059 | 3/20 | 0.45 |
| ▸ | AR | P10275 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14190710 | 0.82 | HTT (0.56) | HTTGAAL3MBTL1APPSNCA | |
| SCHEMBL31738413 | 0.82 | CA1 (0.57) | HTTGAAL3MBTL1APPSNCA | |
| SCHEMBL13458048 | 0.79 | RAB9A (0.56) | HTTGAAAPPSNCADYRK1A | |
| SCHEMBL8034150 | 0.78 | SNCA (0.78) | HTTGAAL3MBTL1APPSNCA | |
| SCHEMBL12566875 | 0.76 | INSR (0.42) | L3MBTL1APPSNCAMAPT | |
| SCHEMBL8355849 | 0.76 | SNCA (0.62) | HTTGAAL3MBTL1APPSNCA | |
| SCHEMBL8355851 | 0.76 | SNCA (0.62) | HTTGAAL3MBTL1APPSNCA | |
| SCHEMBL17954786 | 0.76 | APP (0.67) | HTTGAAL3MBTL1APPSNCA | |
| SCHEMBL2217147 | 0.75 | HTT (0.66) | HTTGAAL3MBTL1APPCA12 | |
| SCHEMBL12545463 | 0.75 | CYP1A2 (0.59) | HTTAPPDYRK1AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010024463-A1 | THERMOPLASTIC RESIN, ORGANIC-INORGANIC HYBRID COMPOSITION AND OPTICAL PARTS | FUJIFILM CORPORATION (JP) | 2010-03-04 | — | — | WO | disclosed |