SCHEMBL1345917

SCHEMBL1345917

Cc1ccc(O)c(Cc2cc(C)cc(Cc3cc(C)cc(Cc4cc(C)cc(Cc5cc(C)ccc5O)c4O)c3O)c2O)c1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AMY1A P0DUB6 1/20 1.00
HIF1A Q16665 4/20 0.55
CYP2C9 P11712 3/20 0.55
CYP2C19 P33261 3/20 0.55
SMN1; SMN2 Q16637 2/20 0.53
HSPA5 P11021 3/20 0.50
TRPA1 O75762 1/20 0.48
ALOX15 P16050 4/20 0.47
LMNA P02545 3/20 0.47
HPGD P15428 3/20 0.47
HTT P42858 2/20 0.47
MEN1 O00255 2/20 0.47
MAPT P10636 2/20 0.47
ALOX12 P18054 2/20 0.47
KMT2A Q03164 2/20 0.47
SLC22A1 O15245 1/20 0.47
USP2 O75604 1/20 0.47
HSP90AA1 P07900 1/20 0.47
CYP3A4 P08684 1/20 0.47
HSPD1 P10809 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1345563 1.00 AMY1A (1.00) AMY1AHIF1ACYP2C9CYP2C19SMN1; SMN2
SCHEMBL218957 1.00 AMY1A (1.00) AMY1AHIF1ACYP2C9CYP2C19SMN1; SMN2
SCHEMBL29623092 1.00 AMY1A (1.00) AMY1AHIF1ACYP2C9CYP2C19SMN1; SMN2
SCHEMBL18352 1.00 AMY1A (1.00) AMY1AHIF1ACYP2C9CYP2C19SMN1; SMN2
SCHEMBL30320292 1.00 AMY1A (1.00) AMY1AHIF1ACYP2C9CYP2C19SMN1; SMN2
SCHEMBL3820165 1.00 AMY1A (1.00) AMY1AHIF1ACYP2C9CYP2C19SMN1; SMN2
SCHEMBL1345514 1.00 AMY1A (1.00) AMY1AHIF1ACYP2C9CYP2C19SMN1; SMN2
Phosphine SCHEMBL26919025 0.98 AMY1A (0.96) AMY1AHIF1ACYP2C9CYP2C19SMN1; SMN2
Formaldehyde SCHEMBL28912209 0.94 AMY1A (0.89) AMY1AHIF1ACYP2C9CYP2C19SMN1; SMN2
SCHEMBL8078719 0.93 AMY1A (0.86) AMY1AHIF1ACYP2C9CYP2C19SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9562124-B2 Thermo-oxidatively stable, side chain polyether functionalized polynorbornenes for microelectronic and optoelectronic devices and assemblies thereof PROMERUS, LLC (US) 2017-02-07 US claimed
US-20160319060-A1 Thermo-oxidatively Stable, Side Chain Polyether Functionalized Polynorbornenes for Microelectronic and Optoelectronic Devices and Assemblies Thereof PROMERUS, LLC (US) 2016-11-03 US claimed
US-9562124-B2 Thermo-oxidatively stable, side chain polyether functionalized polynorbornenes for microelectronic and optoelectronic devices and assemblies thereof PROMERUS, LLC (US) 2017-02-07 US disclosed
US-20160319060-A1 Thermo-oxidatively Stable, Side Chain Polyether Functionalized Polynorbornenes for Microelectronic and Optoelectronic Devices and Assemblies Thereof PROMERUS, LLC (US) 2016-11-03 US disclosed
US-9425404-B2 Thermo-oxidatively stable, side chain polyether functionalized polynorbornenes for microelectronic and optoelectronic devices and assemblies thereof PROMERUS, LLC (US) 2016-08-23 US disclosed
EP-1724119-B1 DEVELOPER MIXTURE FOR THERMAL RECORDING MATERIALS AND THERMAL RECORDING MATERIALS MITSUBISHI CHEM CORP (JP) 2014-11-19 EP disclosed
WO-2013109529-A1 THERMO-OXIDATIVELY STABLE, SIDE CHAIN POLYETHER FUNCTIONALIZED POLYNORBORNENES FOR MICROELECTRONIC AND OPTOELECTRONIC DEVICES AND ASSEMBLIES THEREOF PROMERUS LLC (US) 2013-07-25 WO disclosed
US-20130181199-A1 Thermo-oxidatively Stable, Side Chain Polyether Functionalized Polynorbornenes for Microelectronic and Optoelectronic Devices and Assemblies Thereof SUMITOMO BAKELITE CO., LTD. (JP) 2013-07-18 US disclosed
US-8062993-B2 Developer mixture for thermal recording materials and thermal recording materials API CORPORATION (JP) 2011-11-22 US disclosed
US-7534547-B2 Optically active compound and photosensitive resin composition OSAKA GAS COMPANY LIMITED (JP) 2009-05-19 US disclosed
US-20070173407-A1 Developer mixture for thermal recording materials and thermal recording materials API CORPORATION (JP) 2007-07-26 US disclosed
EP-1724119-A1 DEVELOPER MIXTURE FOR THERMAL RECORDING MATERIALS AND THERMAL RECORDING MATERIALS API Corporation (JP) 2006-11-22 EP disclosed
EP-1375463-A1 OPTICALLY ACTIVE COMPOUND AND PHOTOSENSITIVE RESIN COMPOSITION Kansai Research Institute, Inc. (JP) 2004-01-02 EP disclosed
US-20030211421-A1 Optically active compound and photosensitive resin composition KRI, INC. (JP) 2003-11-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030211421-A1 Optically active compound and photosensitive resin composition ARCN1, RAD51, PAM AMY1A 2387/4885HIF1A 72/4885CYP2C9 1479/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.