Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DUT | P33316 | 14/20 | 0.37 |
| ▸ | IDO1 | P14902 | 1/20 | 0.35 |
| ▸ | TDO2 | P48775 | 1/20 | 0.35 |
| ▸ | GRM2 | Q14416 | 2/20 | 0.33 |
| ▸ | PDE4A | P27815 | 1/20 | 0.33 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.33 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.33 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15864646 | 0.83 | DUT (0.47) | DUTIDO1TDO2GRM2 | |
| SCHEMBL29363809 | 0.83 | DUT (0.47) | DUTIDO1TDO2GRM2 | |
| SCHEMBL17492963 | 0.83 | DUT (0.47) | DUTIDO1TDO2GRM2 | |
| SCHEMBL15864648 | 0.80 | DUT (0.39) | DUTIDO1TDO2GRM2 | |
| SCHEMBL21325251 | 0.76 | DUT (0.45) | DUTIDO1TDO2GRM2 | |
| SCHEMBL20188078 | 0.76 | DUT (0.41) | DUTIDO1TDO2GRM2 | |
| SCHEMBL20204783 | 0.74 | DUT (0.53) | DUTIDO1TDO2GRM2 | |
| SCHEMBL20347946 | 0.73 | DUT (0.46) | DUTIDO1TDO2GRM2 | |
| SCHEMBL16891348 | 0.73 | DUT (0.46) | DUTIDO1TDO2GRM2 | |
| SCHEMBL2304488 | 0.71 | SCN8A (0.43) | DUTIDO1GRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010023946-A1 | NOVEL URACIL COMPOUND HAVING NITROGENATED HETEROCYCLIC RING OR SALT THEREOF | 大鵬薬品工業株式会社 (JP) | 2010-03-04 | — | — | WO | disclosed |