SCHEMBL2304488

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1409593	0.86	DUT (0.45)	DUTIDO1GRM2HTR2AHTR2C
	SCHEMBL20347946	0.86	DUT (0.46)	DUTIDO1GRM2HTR2AHTR2C
	SCHEMBL21325251	0.83	DUT (0.45)	DUTIDO1GRM2HTR2AHTR2C
	SCHEMBL14145336	0.83	SCN8A (0.42)	SCN8ASCN10ALPLLIPGHTR2A
	SCHEMBL14145363	0.83	SCN8A (0.42)	SCN8ASCN10ALPLLIPGGRM2
	SCHEMBL23212111	0.83	SCN8A (0.45)	SCN8ASCN10ALPLLIPGHTR2A
	SCHEMBL23212110	0.83	SCN8A (0.45)	SCN8ASCN10ALPLLIPGSLC6A9
	SCHEMBL22414494	0.82	DUT (0.45)	DUTIDO1GRM2HTR2AHTR2C
	SCHEMBL12696881	0.81	DUT (0.44)	DUTIDO1GRM2HTR2AHTR2C
	SCHEMBL20204783	0.81	DUT (0.53)	DUTIDO1GRM2RIPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.