SCHEMBL13460501

SCHEMBL13460501

COc1cccc(CCN=[N+]=[N-])c1

nearest known ligand 0.57

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
TAAR1 Q96RJ0 3/20 0.57
CHRM2 P08172 3/20 0.54
CHRM1 P11229 3/20 0.54
CHRM3 P20309 3/20 0.54
SIGMAR1 Q99720 1/20 0.51
AOC3 Q16853 1/20 0.51
HRH3 Q9Y5N1 1/20 0.49
IDO1 P14902 2/20 0.49
AGXT P21549 2/20 0.49
MTNR1A P48039 1/20 0.46
MTNR1B P49286 1/20 0.46
ABCB1 P08183 1/20 0.46
HTR1A P08908 1/20 0.46
DRD2 P14416 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16401448 0.85 TAAR1 (0.50) TAAR1CHRM2CHRM1CHRM3SIGMAR1
SCHEMBL30394051 0.85 TAAR1 (0.50) TAAR1CHRM2CHRM1CHRM3SIGMAR1
SCHEMBL18179858 0.82 CYP19A1 (0.46) TAAR1
SCHEMBL7864651 0.81 TAAR1 (0.62) TAAR1CHRM2CHRM1CHRM3SIGMAR1
SCHEMBL13460379 0.80 ADRB2 (0.40) TAAR1CHRM2CHRM1CHRM3AOC3
SCHEMBL30080050 0.80 TAAR1 (0.77) TAAR1CHRM2CHRM1CHRM3SIGMAR1
SCHEMBL723511 0.80 TAAR1 (0.77) TAAR1CHRM2CHRM1CHRM3SIGMAR1
SCHEMBL9608846 0.79 TAAR1 (0.61) TAAR1CHRM2CHRM1CHRM3SIGMAR1
SCHEMBL13460492 0.79 TAAR1 (0.52) TAAR1SIGMAR1AOC3HRH3IDO1
SCHEMBL15042247 0.77 SIGMAR1 (0.38) TAAR1SIGMAR1DRD2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2019238057-A1 APPLICATION OF FSO2N3 IN PREPARATION OF AZIDE 中国科学院上海有机化学研究所 2019-12-19 WO disclosed
WO-2010023946-A1 NOVEL URACIL COMPOUND HAVING NITROGENATED HETEROCYCLIC RING OR SALT THEREOF 大鵬薬品工業株式会社 (JP) 2010-03-04 WO disclosed