Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G4B | P0C869 | 2/20 | 0.58 |
| ▸ | SMPD1 | P17405 | 4/20 | 0.58 |
| ▸ | TSHR | P16473 | 2/20 | 0.57 |
| ▸ | POLB | P06746 | 1/20 | 0.57 |
| ▸ | CASP6 | P55212 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | HPGD | P15428 | 1/20 | 0.56 |
| ▸ | TP53 | P04637 | 1/20 | 0.55 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.54 |
| ▸ | RARB | P10826 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4023882 | 0.92 | POLB (0.64) | PLA2G4BSMPD1TSHRPOLBCASP6 | |
| SCHEMBL7336764 | 0.89 | ALDH1A1 (0.67) | PLA2G4BSMPD1TSHRPOLBCASP6 | |
| SCHEMBL13461243 | 0.88 | KMT2A (0.56) | SMPD1 | |
| SCHEMBL3884522 | 0.88 | SMPD1 (0.68) | PLA2G4BSMPD1TSHRALDH1A1HPGD | |
| SCHEMBL89386 | 0.88 | TSHR (0.69) | PLA2G4BTSHR | |
| SCHEMBL1750327 | 0.88 | TSHR (0.74) | PLA2G4BSMPD1TSHRALDH1A1HPGD | |
| SCHEMBL88998 | 0.88 | CA12 (0.67) | SMPD1TSHRTP53 | |
| SCHEMBL30683868 | 0.88 | TSHR (0.69) | PLA2G4BTSHR | |
| SCHEMBL9512861 | 0.88 | ALDH1A1 (0.65) | PLA2G4BSMPD1TSHRPOLBCASP6 | |
| SCHEMBL1199847 | 0.88 | ALDH1A1 (0.69) | PLA2G4BSMPD1TSHRPOLBCASP6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100056497-A1 | AMIDE DERIVATIVE | DAINIPPON SUMITOMO PHARMA CO., LTD (JP) | 2010-03-04 | — | — | US | disclosed |
| EP-2119702-A1 | AMIDE DERIVATIVE | Dainippon Sumitomo Pharma Co., Ltd. (JP) | 2009-11-18 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100056497-A1 | AMIDE DERIVATIVE | REN, AGTR1, AGTR2 | PLA2G4B 1981/4885SMPD1 1119/4885TSHR 634/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.