Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.63 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.63 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.63 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.61 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.61 |
| ▸ | LGALS1 | P09382 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | CASP2 | P42575 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16384637 | 0.84 | ALDH1A1 (0.63) | ROCK2ROCK1LGALS1POLBALDH1A1 | |
| SCHEMBL13439306 | 0.81 | LGALS1 (0.55) | CYP1A2CYP2D6CYP2C19ROCK2ROCK1 | |
| SCHEMBL11986817 | 0.80 | PPARA (0.52) | SMN1; SMN2KDM4EPOLBALDH1A1LMNA | |
| SCHEMBL10272935 | 0.79 | SMN1; SMN2 (0.62) | SMN1; SMN2KDM4EPOLBALDH1A1LMNA | |
| SCHEMBL22237406 | 0.78 | KDM4E (0.62) | SMN1; SMN2KDM4EPOLBALDH1A1LMNA | |
| SCHEMBL20113556 | 0.77 | ROCK2 (1.00) | CYP2D6ROCK2ROCK1ALDH1A1CYP3A4 | |
| SCHEMBL4487061 | 0.76 | SMN1; SMN2 (0.56) | CYP2D6SMN1; SMN2POLBLMNAMEN1 | |
| SCHEMBL20982727 | 0.76 | CASP2 (0.54) | CYP1A2CYP2D6CYP2C19ROCK2ROCK1 | |
| SCHEMBL10272937 | 0.76 | SMN1; SMN2 (0.58) | SMN1; SMN2KDM4EPOLBALDH1A1LMNA | |
| SCHEMBL10174538 | 0.75 | SMN1; SMN2 (0.56) | CYP1A2CYP2C19SMN1; SMN2KDM4EPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100056530-A1 | GLUCOKINASE ACTIVATORS | ARRAY BIOPHARMA INC. (US) | 2010-03-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100056530-A1 | GLUCOKINASE ACTIVATORS | GCKR, GCK, GALK1 | CYP1A2 2024/4885CYP2D6 1951/4885CYP2C19 2819/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.