Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 1/20 | 0.58 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.58 |
| ▸ | SLC18A3 | Q16572 | 2/20 | 0.53 |
| ▸ | CES2 | O00748 | 1/20 | 0.52 |
| ▸ | CES1 | P23141 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.48 |
| ▸ | CA1 | P00915 | 2/20 | 0.48 |
| ▸ | CA2 | P00918 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | HTR2A | P28223 | 1/20 | 0.46 |
| ▸ | HTR2C | P28335 | 1/20 | 0.46 |
| ▸ | HTR2B | P41595 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4770419 | 0.91 | SRD5A2 (0.59) | MGLLHSD11B1SLC18A3CES2CES1 | |
| SCHEMBL10112217 | 0.91 | MGLL (0.55) | MGLLHSD11B1SLC18A3CES2CES1 | |
| SCHEMBL26622715 | 0.90 | SRD5A2 (0.62) | MGLLHSD11B1SLC18A3CES2CES1 | |
| SCHEMBL14335438 | 0.90 | SRD5A2 (0.62) | MGLLHSD11B1SLC18A3CES2CES1 | |
| SCHEMBL14335831 | 0.86 | MGLL (0.51) | MGLLHSD11B1SLC18A3CES2CES1 | |
| SCHEMBL4673866 | 0.86 | MGLL (0.51) | MGLLHSD11B1SLC18A3CES2CES1 | |
| SCHEMBL1135130 | 0.86 | MEN1 (0.67) | MGLLHSD11B1SLC18A3CES2CES1 | |
| SCHEMBL26622766 | 0.85 | MGLL (0.47) | MGLLHSD11B1SLC18A3CES2CES1 | |
| Bromide SCHEMBL10966041 | 0.85 | MEN1 (0.65) | MGLLHSD11B1SLC18A3CES2CES1 | |
| Hydrochloric Acid SCHEMBL11518027 | 0.85 | MEN1 (0.70) | MGLLHSD11B1SLC18A3CES2CES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 175 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115584014-A | Ladder-shaped polymer material with heat-resisting and fluorescent characteristics and preparation method thereof | 大连理工大学 | 2023-01-10 | — | — | CN | claimed |
| US-12528802-B2 | Heterocyclic compound | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2026-01-20 | — | — | US | disclosed |
| US-20260008782-A1 | HYDANTOIN MODULATORS OF CHOLESTEROL BIOSYNTHESIS AND THEIR USE FOR PROMOTING REMYELINATION | CONVELO THERAPEUTICS, INC. | 2026-01-08 | — | — | US | disclosed |
| US-20250333406-A1 | SULFONYL CYCLIC DERIVATIVES, AND COMPOSITIONS AND METHODS THEREOF | LYSOWAY THERAPEUTICS INC (US) | 2025-10-30 | — | — | US | disclosed |
| CN-119998288-A | Hydantoin modulators of cholesterol biosynthesis and their use for promoting remyelination | 基因泰克公司 | 2025-05-13 | — | — | CN | disclosed |
| US-20250066355-A1 | HISTONE DEMETHYLASE INHIBITORS | CELGENE QUANTICEL RESEARCH, INC. (US) | 2025-02-27 | — | — | US | disclosed |
| US-12172998-B2 | Histone demethylase inhibitors | CELGENE QUANTICEL RESEARCH, INC. (US) | 2024-12-24 | — | — | US | disclosed |
| CN-115894447-B | METTL3 inhibitors and uses thereof | 成都先导药物开发股份有限公司 | 2024-10-01 | — | — | CN | disclosed |
| CN-115784857-B | 4-Fluorophenyl cyclopropyl ketone-14C and preparation method thereof | 长沙贝塔医药科技有限公司 | 2024-05-24 | — | — | CN | disclosed |
| US-20240115711-A1 | Novel Bifunctional Molecules For Targeted Protein Degradation | AMPHISTA THERAPEUTICS LIMITED (GB) | 2024-04-11 | — | — | US | disclosed |
| CN-1192739-A | N-heteroaryl-pyridinesulfonamide derivatives and their use as endothelin antagonists | ZENECA LTD (GB) | 1998-09-09 | — | — | CN | disclosed |
| US-5763450-A | BACTERICIDES; TREATMENT OF INFECTIOUS DISEASES | HOFFMANN-LA ROCHE INC. (US) | 1998-06-09 | — | — | US | disclosed |
| EP-0832082-A1 | N-HETEROARYL-PYRIDINESULFONAMIDE DERIVATIVES AND THEIR USE AS ENDOTHELIN ANTAGONISTS | ZENECA LIMITED (GB) | 1998-04-01 | — | — | EP | disclosed |
| EP-0793656-A1 | NOVEL BENZYL PYRIMIDINES | F. HOFFMANN-LA ROCHE AG (CH) | 1997-09-10 | — | — | EP | disclosed |
| WO-1996040681-A1 | N-HETEROARYL-PYRIDINESULFONAMIDE DERIVATIVES AND THEIR USE AS ENDOTHELIN ANTAGONISTS | ZENECA LIMITED (GB) | 1996-12-19 | — | — | WO | disclosed |
| CN-1134696-A | Substituted 5-membered heterocycles, process for their preparation and their use | CASSELLA FARBWERKE MAINKUR AG (DE) | 1996-10-30 | — | — | CN | disclosed |
| EP-0729460-A1 | SUBSTITUTED 5-RING HETEROCYCLES, THEIR PREPARATION AND THEIR USE | HOECHST AKTIENGESELLSCHAFT (DE) | 1996-09-04 | — | — | EP | disclosed |
| WO-1996016046-A2 | NOVEL BENZYL PYRIMIDINES | F. HOFFMANN-LA ROCHE AG (CH) | 1996-05-30 | — | — | WO | disclosed |
| WO-1995014008-A1 | SUBSTITUTED 5-RING HETEROCYCLES, THEIR PREPARATION AND THEIR USE | HOECHST AKTIENGESELLSCHAFT (DE) | 1995-05-26 | — | — | WO | disclosed |
| US-4137324-A | Optionally substituted phenyl-α-cyclopropyl acetic acid esters and use as insecticides | NATIONAL RESEARCH DEVELOPMENT CORPORATION (GB) | 1979-01-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12172998-B2 | Histone demethylase inhibitors | KDM1B, KDM1A, KDM5C | MGLL 3432/4885HSD11B1 1574/4885SLC18A3 4250/4885 |
| US-20260008782-A1 | HYDANTOIN MODULATORS OF CHOLESTEROL BIOSYNTHESIS AND THEIR USE FOR PROMOTING REMYELINATION | SGMS1, MAG, SGMS2 | MGLL 292/4885HSD11B1 258/4885SLC18A3 671/4885 |
| US-12528802-B2 | Heterocyclic compound | GBA2, GBA1, GALC | MGLL 325/4885HSD11B1 1530/4885SLC18A3 662/4885 |
| US-20250333406-A1 | SULFONYL CYCLIC DERIVATIVES, AND COMPOSITIONS AND METHODS THEREOF | STOML2, ATP2A3, ATP2A1 | MGLL 165/4885HSD11B1 3992/4885SLC18A3 853/4885 |
| US-20240115711-A1 | Novel Bifunctional Molecules For Targeted Protein Degradation | PSMG3, MYCBP2, PSME2 | MGLL 2687/4885HSD11B1 4523/4885SLC18A3 4079/4885 |
| US-20250066355-A1 | HISTONE DEMETHYLASE INHIBITORS | KDM1B, KDM1A, KDM5C | MGLL 3432/4885HSD11B1 1574/4885SLC18A3 4250/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.