Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 4/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.35 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.35 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.35 |
| ▸ | BRD4 | O60885 | 1/20 | 0.34 |
| ▸ | ADORA2B | P29275 | 3/20 | 0.33 |
| ▸ | GSK3B | P49841 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6859504 | 0.88 | PTGS2 (0.41) | PTGS2MEN1KMT2AGSK3BALDH1A1 | |
| SCHEMBL1556973 | 0.84 | PTGS2 (0.54) | PTGS2PTPN1PTPN6PTPN11GSK3B | |
| SCHEMBL8759244 | 0.83 | GSK3B (0.43) | PTGS2GSK3B | |
| SCHEMBL12173264 | 0.77 | LMNA (0.43) | PTGS2MEN1KMT2APTPN1PTPN6 | |
| SCHEMBL6693898 | 0.76 | PTGS2 (0.45) | PTGS2GSK3B | |
| SCHEMBL13883926 | 0.74 | PTGS2 (0.44) | PTGS2GSK3B | |
| SCHEMBL18138113 | 0.74 | APP (0.35) | PTGS2MEN1KMT2AALDH1A1 | |
| SCHEMBL13592016 | 0.74 | PTGS2 (0.34) | PTGS2GSK3BMMP2MMP9 | |
| SCHEMBL13524801 | 0.72 | KDM4E (0.35) | PTGS2MEN1KMT2AL3MBTL1GSK3B | |
| SCHEMBL7068310 | 0.72 | PTGS2 (0.51) | PTGS2MEN1HTTKMT2AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2370523-B1 | FLOCCULATION RESISTANT DIKETOPYRROLOPYRROLE PIGMENT PREPARATIONS | CLARIANT FINANCE BVI LTD (VG) | 2012-10-17 | — | — | EP | disclosed |