Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 2/20 | 0.41 |
| ▸ | GSK3B | P49841 | 9/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | GSK3A | P49840 | 1/20 | 0.34 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | TDP2 | O95551 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8759244 | 0.94 | GSK3B (0.43) | PTGS2GSK3BLMNAGAAMAPT | |
| SCHEMBL13464784 | 0.88 | PTGS2 (0.45) | PTGS2GSK3BALDH1A1KDM4EMEN1 | |
| SCHEMBL6693898 | 0.86 | PTGS2 (0.45) | PTGS2GSK3B | |
| SCHEMBL18138113 | 0.84 | APP (0.35) | PTGS2GAAALDH1A1MEN1KMT2A | |
| SCHEMBL13883926 | 0.84 | PTGS2 (0.44) | PTGS2GSK3B | |
| SCHEMBL7068310 | 0.81 | PTGS2 (0.51) | PTGS2GSK3BLMNAGAAALDH1A1 | |
| SCHEMBL6857980 | 0.81 | PKM (0.36) | PTGS2GSK3BLMNAGAAALDH1A1 | |
| SCHEMBL91966 | 0.79 | PTGS2 (0.50) | PTGS2GSK3BRECQLGAAALDH1A1 | |
| SCHEMBL22591650 | 0.77 | PTGS2 (0.34) | PTGS2ALDH1A1MEN1HPGDKMT2A | |
| SCHEMBL13907349 | 0.76 | PTGS2 (0.32) | PTGS2GSK3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6790884-B2 | NONDEFORMING; FOR CRYSTALLINE PLASTICS | CIBA SPECIALTY CHEMICALS CORPORATION | 2004-09-14 | — | — | US | disclosed |