Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 6/20 | 0.45 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.41 |
| ▸ | NR1H3 | Q13133 | 2/20 | 0.41 |
| ▸ | GSK3B | P49841 | 5/20 | 0.40 |
| ▸ | EP300 | Q09472 | 1/20 | 0.34 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.33 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.33 |
| ▸ | PDE5A | O76074 | 1/20 | 0.33 |
| ▸ | CASP3 | P42574 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13883926 | 0.98 | PTGS2 (0.44) | PTGS2NR1H2NR1H3GSK3BPDE5A | |
| SCHEMBL8759244 | 0.93 | GSK3B (0.43) | PTGS2NR1H2NR1H3GSK3B | |
| SCHEMBL18138113 | 0.86 | APP (0.35) | PTGS2 | |
| SCHEMBL6859504 | 0.86 | PTGS2 (0.41) | PTGS2GSK3B | |
| SCHEMBL21419681 | 0.81 | GSK3B (0.36) | PTGS2GSK3BSIRT2SIRT1 | |
| SCHEMBL19304186 | 0.81 | PTGS2 (0.37) | PTGS2GSK3B | |
| SCHEMBL5070001 | 0.80 | NR1H2 (0.52) | PTGS2NR1H2NR1H3SIRT2SIRT1 | |
| SCHEMBL5124277 | 0.80 | GSK3B (0.41) | NR1H2NR1H3GSK3B | |
| SCHEMBL5124396 | 0.79 | GRK5 (0.42) | PTGS2NR1H2NR1H3GSK3B | |
| SCHEMBL22591650 | 0.79 | PTGS2 (0.34) | PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230050869-A1 | THERMOELECTRIC CONVERSION MATERIAL, AND THERMOELECTRIC CONVERSION ELEMENT PREPARED THEREWITH | TOYO INK SC HOLDINGS CO., LTD. (JP) | 2023-02-16 | — | — | US | disclosed |
| US-8883889-B2 | Pigment compositions comprising pyrrolo[3,4-c]pyrroles | BASF SE (DE) | 2014-11-11 | — | — | US | disclosed |
| US-8883889-B2 | Pigment compositions comprising pyrrolo[3,4-c]pyrroles | BASF SE (DE) | 2014-11-11 | — | — | US | disclosed |
| US-20070117889-A1 | Process for the direct preparation of pyrrolo[3,4-C]pyrroles | RUFFIEUX VINCENT | 2007-05-24 | — | — | US | disclosed |
| US-20070117889-A1 | Process for the direct preparation of pyrrolo[3,4-C]pyrroles | RUFFIEUX VINCENT | 2007-05-24 | — | — | US | disclosed |
| US-7186847-B2 | From a pyrrolidinone compound; coloring high molecular weight material | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 2007-03-06 | — | — | US | disclosed |
| US-7186847-B2 | From a pyrrolidinone compound; coloring high molecular weight material | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 2007-03-06 | — | — | US | disclosed |
| WO-2004092174-A1 | PYRROLOPYRROLES USED AS FLUORESCENT LABELS FOR BIOMOLECULES AND SPHERICAL PARTICLES | CHROMEON GMBH (DE) | 2004-10-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070117889-A1 | Process for the direct preparation of pyrrolo[3,4-C]pyrroles | PAX3, PPOX, FIP1L1 | PTGS2 582/4885NR1H2 4455/4885NR1H3 4488/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.