Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.64 |
| ▸ | POLB | P06746 | 2/20 | 0.64 |
| ▸ | MGLL | Q99685 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.40 |
| ▸ | FABP6 | P51161 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | NAMPT | P43490 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16131141 | 0.90 | ALDH1A1 (0.51) | ALDH1A1POLBMGLLMEN1KMT2A | |
| SCHEMBL16132012 | 0.83 | ALDH1A1 (0.51) | ALDH1A1POLBMEN1KMT2ALMNA | |
| SCHEMBL18368364 | 0.82 | KMT2A (0.54) | ALDH1A1MGLLMEN1KMT2ALMNA | |
| SCHEMBL13279929 | 0.80 | ALDH1A1 (0.48) | ALDH1A1POLBMEN1KMT2ALMNA | |
| SCHEMBL10169265 | 0.80 | ALDH1A1 (0.97) | ALDH1A1POLBMEN1KMT2ALMNA | |
| SCHEMBL13322388 | 0.79 | HSP90AA1 (0.52) | ALDH1A1MGLLKMT2ASMN1; SMN2KDM4E | |
| SCHEMBL12986278 | 0.77 | ALDH1A1 (0.64) | ALDH1A1POLBMEN1KMT2ALMNA | |
| SCHEMBL13436276 | 0.76 | ALDH1A1 (0.43) | ALDH1A1POLBMEN1KMT2ALMNA | |
| SCHEMBL13466403 | 0.76 | PKM (0.47) | ALDH1A1POLBMEN1KMT2ALMNA | |
| SCHEMBL16131150 | 0.74 | MGLL (0.45) | ALDH1A1MGLLMEN1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012142329-A1 | COMPOSITIONS AND THERAPEUTIC USES OF IKK-RELATED KINASE EPSILON AND TANKBINDING KINASE 1 INHIBITORS | MYREXIS, INC. (US) | 2012-10-18 | — | — | WO | disclosed |