Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APLNR | P35414 | 1/20 | 0.52 |
| ▸ | OPRD1 | P41143 | 6/20 | 0.51 |
| ▸ | CAPN1 | P07384 | 2/20 | 0.47 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.47 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.45 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.45 |
| ▸ | RAMP3 | O60896 | 1/20 | 0.45 |
| ▸ | CALCR | P30988 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31386380 | 0.84 | CXCR4 (0.56) | APLNROPRM1OPRK1RAMP3CALCR | |
| SCHEMBL30899148 | 0.82 | NMUR2 (0.50) | APLNROPRD1OPRM1RAMP3CALCR | |
| SCHEMBL17378292 | 0.82 | APLNR (0.47) | APLNROPRD1CAPN1RAMP3CALCR | |
| SCHEMBL30636809 | 0.82 | OPRD1 (0.50) | OPRD1OPRM1RAMP3CALCR | |
| SCHEMBL29748654 | 0.81 | NTSR1 (0.50) | APLNROPRD1OPRM1 | |
| SCHEMBL31433200 | 0.81 | RAMP3 (0.51) | APLNROPRD1OPRM1RAMP3CALCR | |
| SCHEMBL30602837 | 0.81 | NTSR1 (0.55) | OPRD1OPRM1 | |
| SCHEMBL29801725 | 0.81 | NTSR2 (0.57) | APLNROPRD1OPRM1 | |
| SCHEMBL30733332 | 0.81 | NTSR2 (0.52) | OPRD1OPRM1RAMP3CALCR | |
| SCHEMBL17370235 | 0.80 | CAPN1 (0.52) | APLNROPRD1CAPN1RAMP3CALCR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8580923-B2 | Self-assembling peptide amphiphiles and related methods for growth factor delivery | NORTHWESTERN UNIVERSITY (US) | 2013-11-12 | — | — | US | disclosed |
| US-20120264912-A1 | SELF-ASSEMBLING PEPTIDE AMPHIPHILES AND RELATED METHODS FOR GROWTH FACTOR DELIVERY | NORTHWESTERN UNIVERSITY (US) | 2012-10-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120264912-A1 | SELF-ASSEMBLING PEPTIDE AMPHIPHILES AND RELATED METHODS FOR GROWTH FACTOR DELIVERY | HDGF, HDGFL3, IAPP | APLNR 13/4885OPRD1 4235/4885CAPN1 2387/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.