Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR2F2 | P24468 | 2/20 | 0.58 |
| ▸ | SLC29A1 | Q99808 | 4/20 | 0.54 |
| ▸ | NPC1 | O15118 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.53 |
| ▸ | CDK1 | P06493 | 1/20 | 0.53 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.53 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.53 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | ABL1 | P00519 | 2/20 | 0.52 |
| ▸ | RIN1 | Q13671 | 2/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13467417 | 0.91 | NR2F2 (0.57) | NR2F2SLC29A1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL13467655 | 0.91 | NPC1 (0.66) | NR2F2SLC29A1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL13467412 | 0.86 | NR2F2 (0.55) | NR2F2SLC29A1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL24600710 | 0.84 | ADORA3 (0.53) | NR2F2SLC29A1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL2036287 | 0.83 | ALDH1A1 (0.55) | NR2F2ADORA3ABL1RIN1 | |
| SCHEMBL19582971 | 0.82 | SLC29A1 (0.77) | SLC29A1ADORA3TP53TDP1 | |
| SCHEMBL14047479 | 0.82 | TP53 (0.65) | NR2F2SLC29A1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL9589282 | 0.82 | ALDH1A1 (0.54) | ADORA3ABL1RIN1 | |
| SCHEMBL9589274 | 0.82 | ALDH1A1 (0.54) | ADORA3ABL1RIN1 | |
| SCHEMBL9587631 | 0.82 | ALDH1A1 (0.54) | ADORA3ABL1RIN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2511283-A1 | N6-SUBSTITUTED ADENOSINE DERIVATIVES, N6-SUBSTITUTED ADENINE DERIVATIVES AND USES THEREOF | INSTITUTE OF MATERIA MEDICA, CHINESE ACADEMY OF MEDICAL SCIENCES (CN) | 2012-10-17 | — | — | EP | disclosed |