Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 2/20 | 0.65 |
| ▸ | PAX8 | Q06710 | 2/20 | 0.65 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.65 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.65 |
| ▸ | LMNA | P02545 | 2/20 | 0.65 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.65 |
| ▸ | MITF | O75030 | 1/20 | 0.65 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.54 |
| ▸ | CDK1 | P06493 | 1/20 | 0.54 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.54 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.54 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.52 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.52 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.52 |
| ▸ | NR2F2 | P24468 | 2/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | ABL1 | P00519 | 3/20 | 0.49 |
| ▸ | RIN1 | Q13671 | 3/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13467655 | 0.85 | NPC1 (0.66) | TP53PAX8ADORA3SMN1; SMN2SLC29A1 | |
| SCHEMBL19583031 | 0.83 | TP53 (0.71) | TP53PAX8ADORA3SMN1; SMN2LMNA | |
| SCHEMBL13467551 | 0.82 | NR2F2 (0.58) | TP53ADORA3SMN1; SMN2SLC29A1CCNB2 | |
| SCHEMBL13467417 | 0.82 | NR2F2 (0.57) | TP53PAX8ADORA3SMN1; SMN2SLC29A1 | |
| SCHEMBL2036287 | 0.81 | ALDH1A1 (0.55) | ADORA3LMNANR2F2ABL1RIN1 | |
| SCHEMBL2390773 | 0.81 | NPC1 (0.68) | TP53PAX8ADORA3SMN1; SMN2LMNA | |
| SCHEMBL9589274 | 0.81 | ALDH1A1 (0.54) | ADORA3LMNAADORA2AADORA2BADORA1 | |
| SCHEMBL9589282 | 0.81 | ALDH1A1 (0.54) | ADORA3LMNAADORA2AADORA2BADORA1 | |
| SCHEMBL9587631 | 0.81 | ALDH1A1 (0.54) | ADORA3LMNAADORA2AADORA2BADORA1 | |
| SCHEMBL2391367 | 0.80 | SMN1; SMN2 (0.73) | TP53PAX8ADORA3SMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080267948-A1 | Croos-B Structure Binding Compounds | CROSSBETA BIOSCIENCES B.V. (NL) | 2008-10-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080267948-A1 | Croos-B Structure Binding Compounds | CACYBP, TBCB, MYCBP | TP53 2046/4885PAX8 1756/4885ADORA3 1337/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.