Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 3/20 | 0.67 |
| ▸ | MAOB | P27338 | 3/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.62 |
| ▸ | TRPV1 | Q8NER1 | 4/20 | 0.62 |
| ▸ | NPC1 | O15118 | 4/20 | 0.62 |
| ▸ | RAB9A | P51151 | 4/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.62 |
| ▸ | HPGD | P15428 | 3/20 | 0.62 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.62 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.62 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.62 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.62 |
| ▸ | CTSD | P07339 | 1/20 | 0.62 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.62 |
| ▸ | MAOA | P21397 | 1/20 | 0.62 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.62 |
| ▸ | DHODH | Q02127 | 1/20 | 0.62 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.62 |
| ▸ | LMNA | P02545 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10932270 | 0.81 | ALOX5 (1.00) | ALOX5MAOBALDH1A1SMN1; SMN2TRPV1 | |
| SCHEMBL29738484 | 0.81 | ALOX5 (1.00) | ALOX5MAOBALDH1A1SMN1; SMN2TRPV1 | |
| SCHEMBL17340469 | 0.81 | ALOX5 (1.00) | ALOX5MAOBALDH1A1SMN1; SMN2TRPV1 | |
| SCHEMBL29738485 | 0.80 | ALOX5 (0.97) | ALOX5MAOBALDH1A1SMN1; SMN2TRPV1 | |
| SCHEMBL4199453 | 0.79 | ALDH1A1 (0.65) | ALOX5MAOBALDH1A1SMN1; SMN2TRPV1 | |
| SCHEMBL4199451 | 0.79 | ALDH1A1 (0.65) | ALOX5MAOBALDH1A1SMN1; SMN2TRPV1 | |
| SCHEMBL23728298 | 0.79 | ALOX5 (0.72) | ALOX5MAOBALDH1A1SMN1; SMN2TRPV1 | |
| SCHEMBL4919407 | 0.79 | ALOX5 (0.72) | ALOX5MAOBALDH1A1SMN1; SMN2TRPV1 | |
| SCHEMBL29738482 | 0.77 | ALDH1A1 (0.70) | ALOX5MAOBALDH1A1SMN1; SMN2TRPV1 | |
| SCHEMBL29738483 | 0.77 | ALOX5 (0.66) | ALOX5MAOBALDH1A1SMN1; SMN2TRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220000964-A1 | Compositions and Methods for Regulating Homeostasis of Chondrocytes, Extracellular Matrix, Articular Cartilage, and Phenotype of Arthritis | UNIGEN, INC. (US) | 2022-01-06 | — | — | US | disclosed |
| US-8840938-B2 | Bioavailability enhancing composition | WARNOCK W MATTHEW (US) | 2014-09-23 | — | — | US | disclosed |
| US-20120263808-A1 | BIOAVAILABILITY ENHANCING COMPOUND | WARNOCK W MATTHEW (US) | 2012-10-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220000964-A1 | Compositions and Methods for Regulating Homeostasis of Chondrocytes, Extracellular Matrix, Articular Cartilage, and Phenotype of Arthritis | COL2A1, COL1A1, CKAP4 | ALOX5 3465/4885MAOB 3518/4885ALDH1A1 1095/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.