Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP51A1 | Q16850 | 4/20 | 0.45 |
| ▸ | NPC1 | O15118 | 4/20 | 0.44 |
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | CASP1 | P29466 | 1/20 | 0.44 |
| ▸ | HBB | P68871 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.42 |
| ▸ | KDM1A | O60341 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13882617 | 0.88 | CA1 (0.47) | CYP51A1CA1CA2CA5ACA9 | |
| SCHEMBL23854165 | 0.88 | CA1 (0.47) | CYP51A1CA1CA2CA5ACA9 | |
| SCHEMBL13649287 | 0.81 | — | — | |
| SCHEMBL18130122 | 0.78 | NQO2 (0.48) | NPC1MAPTRAB9ASMN1; SMN2HPGD | |
| SCHEMBL18130123 | 0.78 | NQO2 (0.48) | NPC1MAPTRAB9ASMN1; SMN2HPGD | |
| SCHEMBL24211777 | 0.78 | CYP19A1 (0.48) | CYP51A1NPC1MAPTRAB9ASMN1; SMN2 | |
| SCHEMBL28674817 | 0.78 | ALOX5 (0.52) | CYP51A1MAPTSMN1; SMN2CYP3A4CYP2D6 | |
| SCHEMBL18845153 | 0.76 | CA1 (0.41) | CYP51A1CA1CA2CA5ACA9 | |
| SCHEMBL13668357 | 0.76 | TP53 (0.42) | CYP51A1KDM4ECYP3A4ALDH1A1CA1 | |
| SCHEMBL29443898 | 0.76 | CA1 (0.41) | CYP51A1CA1CA2CA5ACA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8772048-B2 | Fluorogenic compounds converted to fluorophores by photochemical or chemical means and their use in biological systems | KENT STATE UNIVERSITY (US) | 2014-07-08 | — | — | US | disclosed |
| US-20120190098-A1 | FLUOROGENIC COMPOUNDS CONVERTED TO FLUOROPHORES BY PHOTOCHEMICAL OR CHEMICAL MEANS AND THEIR USE IN BIOLOGICAL SYSTEMS | LELAND STANFORD JUNIOR UNIVERSITY (US) | 2012-07-26 | — | — | US | disclosed |
| US-8153446-B2 | Fluorogenic compounds converted to fluorophores by photochemical or chemical means and their use in biological systems | KENT STATE UNIVERSITY (US) | 2012-04-10 | — | — | US | disclosed |
| US-20100029952-A1 | Fluorogenic compounds converted to fluorophores by photochemical or chemical means and their use in biological systems | KENT STATE UNIVERSITY (US) | 2010-02-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120190098-A1 | FLUOROGENIC COMPOUNDS CONVERTED TO FLUOROPHORES BY PHOTOCHEMICAL OR CHEMICAL MEANS AND THEIR USE IN BIOLOGICAL SYSTEMS | MPI, ACR, PFAS | CYP51A1 2557/4885NPC1 3105/4885MAPT 2134/4885 |
| US-20100029952-A1 | Fluorogenic compounds converted to fluorophores by photochemical or chemical means and their use in biological systems | MPI, ACR, PFAS | CYP51A1 2557/4885NPC1 3105/4885MAPT 2134/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.