Known targets — ChEMBL curated mechanism
ACHECHKACHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGHRH2OPRM1
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.93 |
| ▸ | TP53 | P04637 | 1/20 | 0.93 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.93 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.93 |
| ▸ | TSHR | P16473 | 1/20 | 0.93 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.93 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.93 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.93 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.93 |
| ▸ | SLC22A1 | O15245 | 3/20 | 0.87 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.80 |
| ▸ | DNM1 | Q05193 | 7/20 | 0.78 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL5084980 | 1.00 | ALDH1A1 (0.93) | ALDH1A1TP53CYP3A4ALOX15TSHR | |
| Bromide SCHEMBL5085227 | 1.00 | ALDH1A1 (0.93) | ALDH1A1TP53CYP3A4ALOX15TSHR | |
| Bromide SCHEMBL5087210 | 1.00 | ALDH1A1 (0.93) | ALDH1A1TP53CYP3A4ALOX15TSHR | |
| Bromide SCHEMBL2733876 | 1.00 | ALDH1A1 (0.93) | ALDH1A1TP53CYP3A4ALOX15TSHR | |
| Bromide SCHEMBL5088202 | 1.00 | ALDH1A1 (0.93) | ALDH1A1TP53CYP3A4ALOX15TSHR | |
| Bromide SCHEMBL3028771 | 1.00 | ALDH1A1 (0.93) | ALDH1A1TP53CYP3A4ALOX15TSHR | |
| Bromide SCHEMBL8586767 | 1.00 | ALDH1A1 (0.93) | ALDH1A1TP53CYP3A4ALOX15TSHR | |
| Bromide SCHEMBL5085187 | 1.00 | ALDH1A1 (0.93) | ALDH1A1TP53CYP3A4ALOX15TSHR | |
| Bromide SCHEMBL1507558 | 1.00 | ALDH1A1 (0.93) | ALDH1A1TP53CYP3A4ALOX15TSHR | |
| Bromide SCHEMBL3916850 | 1.00 | ALDH1A1 (0.93) | ALDH1A1TP53CYP3A4ALOX15TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 285 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12291459-B2 | Precipitated silica and process for its manufacture | RHODIA OPERATIONS (FR) | 2025-05-06 | — | — | US | claimed |
| CN-119461609-A | Polymeric coagulant, and preparation method and application thereof | 北京万水净水剂有限公司 | 2025-02-18 | — | — | CN | claimed |
| CN-119386926-A | For CO2/H2Preparation method and application of catalyst for efficiently synthesizing p-aminophenol by water system | 西安凯立新材料股份有限公司 | 2025-02-07 | — | — | CN | claimed |
| CN-115490991-B | High-performance crystal dropping glue and application thereof | 无锡嘉联电子材料有限公司 | 2024-10-29 | — | — | CN | claimed |
| CN-117986967-A | Moisture-cured epoxy paint under marine condition | 浙江鱼童新材料股份有限公司 | 2024-05-07 | — | — | CN | claimed |
| CN-113402437-B | Novel method for synthesizing dietary supplement melatonin | 河北维达康生物科技有限公司 | 2023-07-14 | — | — | CN | claimed |
| CN-113735693-B | Synthesis method of resveratrol dimethyl ether | 河北维达康生物科技有限公司 | 2023-07-14 | — | — | CN | claimed |
| CN-116262623-A | Metal modified hierarchical porous high-silicon Y molecular sieve and preparation method and application thereof | 中国科学院大连化学物理研究所 | 2023-06-16 | — | — | CN | claimed |
| CN-114014829-B | Method for synthesizing 7,4' -dimethylnaringenin | 河北维达康生物科技有限公司 | 2023-03-07 | — | — | CN | claimed |
| CN-115732773-A | Lithium battery thermal runaway suppression assembly and application thereof | 辉能科技股份有限公司 | 2023-03-03 | — | — | CN | claimed |
| US-20040087759-A1 | Fluorinated thermoset polyurethane elastomers prepared from polyether prepolymers formed mono-substituted fluorinated oxetane monomers | AEROJET ROCKETDYNE, INC. (F/K/A AEROJET-GENERAL CORPORATION) | 2004-05-06 | — | — | US | claimed |
| EP-0859970-B1 | BISTABLE LIQUID CRYSTAL DISPLAY DEVICE | NEMOPTIC S A (FR) | 2003-07-02 | — | — | EP | claimed |
| US-6327017-B2 | Bistable liquid crystal display device in which nematic liquid crystal has monostable anchorings | NEMOPTIC S.A. (FR) | 2001-12-04 | — | — | US | claimed |
| US-20010012080-A1 | BISTABLE LIQUID CRYSTAL DISPLAY DEVICE | CDC PROPRIETE INTELLECTUELLE (FR) | 2001-08-09 | — | — | US | claimed |
| US-6037483-A | CHARGING REACTION VESSEL WITH AQUEOUS MIXTURE OF MONO-SUBSTITURED OXETANE, FLUOROALCOHOL, PHASE TRANSFER CATALYST AND STRONG BASE TO FORM REACTION MIXTURE; HEATING UNTIL REACTION IS COMPLETE | AEROJET-GENERAL CORPORATION (US) | 2000-03-14 | — | — | US | claimed |
| CN-1196127-A | Bistable liquid crystal display device | CENTRE NAT RECH SCIENT (FR) | 1998-10-14 | — | — | CN | claimed |
| EP-0811004-A4 | MONO-SUBSTITUTED FLUORINATED OXETANE MONOMERS | AEROJET GENERAL CO (US) | 1998-09-30 | — | — | EP | claimed |
| EP-0811004-A1 | MONO-SUBSTITUTED FLUORINATED OXETANE MONOMERS | AEROJET-GENERAL CORPORATION (US) | 1997-12-10 | — | — | EP | claimed |
| US-5654450-A | THERMOPLASTIC RESIN INTERMEDIATES; TEAR STRENGTH, ADHESION | AEROJET-GENERAL CORPORATION (US) | 1997-08-05 | — | — | US | claimed |
| WO-1996021657-A1 | MONO-SUBSTITUTED FLUORINATED OXETANE MONOMERS | AEROJET-GENERAL CORPORATION (US) | 1996-07-18 | — | — | WO | claimed |